Wound treatment on a diabetic rat model by a 808 nm diode laser

Pik Suan Lau, Noriah Bidin, Ganesan Krishnan, Sana Mohammed Anaybbaleg, Faridah M. Marsin, Mohamad Bin Md Sum, Harzi Baktiar, Zaleha Nassir, Pek Lian Chong, Asmah Hamid

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This paper presents a study on the effect of laser irradiation on wound healing. 808 nm diode laser was employed to facilitate the healing of impaired wounds in experimental diabetes using a rat model. Diabetes was induced in male rats by a streptozotocin injection with a dose of 60 mg kg<sup>-1</sup>. The disease was verified via measurement of the blood glucose level, which was set having 20 mmol L<sup>-1</sup> stability. The rats were randomly distributed into two groups; one served as a control group and the other group was treated with the laser. The power density of the laser used was 0.5 W cm<sup>-2</sup> and the wounds were treated for 8 d with the contact time of one second daily. The energy density used was 0.5 J cm<sup>-2</sup>. The healing progress was recorded via a digital camera. The recorded images were then transferred into Inspector Matrox and image J programs for the accurate measurement of the healing area. The tissue details of the wound were studied through histology. The wound contraction rate of laser therapy group was found to be two times faster than control group. This indicates that the 808 nm diode laser can accelerate the wound healing process.

Original languageEnglish
Article number075601
JournalLaser Physics
Volume25
Issue number7
DOIs
Publication statusPublished - 1 Jul 2015

Fingerprint

rats
Semiconductor lasers
Rats
semiconductor lasers
Medical problems
healing
Lasers
wound healing
Histology
Digital cameras
lasers
Laser beam effects
Glucose
Blood
histology
Tissue
digital cameras
glucose
contraction
blood

Keywords

  • blood glucose
  • diabetic
  • diode laser
  • power density
  • streptozotocin
  • wound

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Industrial and Manufacturing Engineering

Cite this

Lau, P. S., Bidin, N., Krishnan, G., Anaybbaleg, S. M., Marsin, F. M., Sum, M. B. M., ... Hamid, A. (2015). Wound treatment on a diabetic rat model by a 808 nm diode laser. Laser Physics, 25(7), [075601]. https://doi.org/10.1088/1054-660X/25/7/075601

Wound treatment on a diabetic rat model by a 808 nm diode laser. / Lau, Pik Suan; Bidin, Noriah; Krishnan, Ganesan; Anaybbaleg, Sana Mohammed; Marsin, Faridah M.; Sum, Mohamad Bin Md; Baktiar, Harzi; Nassir, Zaleha; Chong, Pek Lian; Hamid, Asmah.

In: Laser Physics, Vol. 25, No. 7, 075601, 01.07.2015.

Research output: Contribution to journalArticle

Lau, PS, Bidin, N, Krishnan, G, Anaybbaleg, SM, Marsin, FM, Sum, MBM, Baktiar, H, Nassir, Z, Chong, PL & Hamid, A 2015, 'Wound treatment on a diabetic rat model by a 808 nm diode laser', Laser Physics, vol. 25, no. 7, 075601. https://doi.org/10.1088/1054-660X/25/7/075601
Lau PS, Bidin N, Krishnan G, Anaybbaleg SM, Marsin FM, Sum MBM et al. Wound treatment on a diabetic rat model by a 808 nm diode laser. Laser Physics. 2015 Jul 1;25(7). 075601. https://doi.org/10.1088/1054-660X/25/7/075601
Lau, Pik Suan ; Bidin, Noriah ; Krishnan, Ganesan ; Anaybbaleg, Sana Mohammed ; Marsin, Faridah M. ; Sum, Mohamad Bin Md ; Baktiar, Harzi ; Nassir, Zaleha ; Chong, Pek Lian ; Hamid, Asmah. / Wound treatment on a diabetic rat model by a 808 nm diode laser. In: Laser Physics. 2015 ; Vol. 25, No. 7.
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