Abstract
Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.
| Original language | English |
|---|---|
| Article number | 2360 |
| Journal | International Journal of Environmental Research and Public Health |
| Volume | 15 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 1 Nov 2018 |
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Keywords
- Anti-inflammatory
- Antibacterial
- Antioxidant
- Collagen
- Polyphenols
- Skin
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Health, Toxicology and Mutagenesis
Cite this
Wound healing properties of selected natural products. / Ibrahim, Nurul ‘Izzah; Wong, Sok Kuan; Naina Mohamed, Isa; Mohamed, Norazlina; Kok Yong, Chin; Soelaiman, Ima Nirwana; Shuid, Ahmad Nazrun.
In: International Journal of Environmental Research and Public Health, Vol. 15, No. 11, 2360, 01.11.2018.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Wound healing properties of selected natural products
AU - Ibrahim, Nurul ‘Izzah
AU - Wong, Sok Kuan
AU - Naina Mohamed, Isa
AU - Mohamed, Norazlina
AU - Kok Yong, Chin
AU - Soelaiman, Ima Nirwana
AU - Shuid, Ahmad Nazrun
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.
AB - Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.
KW - Anti-inflammatory
KW - Antibacterial
KW - Antioxidant
KW - Collagen
KW - Polyphenols
KW - Skin
UR - http://www.scopus.com/inward/record.url?scp=85055617168&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85055617168&partnerID=8YFLogxK
U2 - 10.3390/ijerph15112360
DO - 10.3390/ijerph15112360
M3 - Review article
C2 - 30366427
AN - SCOPUS:85055617168
VL - 15
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
SN - 1661-7827
IS - 11
M1 - 2360
ER -