Wound healing properties of selected natural products

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

Original languageEnglish
Article number2360
JournalInternational Journal of Environmental Research and Public Health
Volume15
Issue number11
DOIs
Publication statusPublished - 1 Nov 2018

Fingerprint

Biological Products
Wound Healing
Tannins
Saponins
Phytochemicals
Volatile Oils
Alkaloids
Flavonoids
Intercellular Signaling Peptides and Proteins
Anti-Inflammatory Agents
Collagen
Antioxidants
Cytokines
Wounds and Injuries
Infection

Keywords

  • Anti-inflammatory
  • Antibacterial
  • Antioxidant
  • Collagen
  • Polyphenols
  • Skin

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

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title = "Wound healing properties of selected natural products",
abstract = "Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.",
keywords = "Anti-inflammatory, Antibacterial, Antioxidant, Collagen, Polyphenols, Skin",
author = "Ibrahim, {Nurul ‘Izzah} and Wong, {Sok Kuan} and {Naina Mohamed}, Isa and Norazlina Mohamed and {Kok Yong}, Chin and Soelaiman, {Ima Nirwana} and Shuid, {Ahmad Nazrun}",
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AU - Ibrahim, Nurul ‘Izzah

AU - Wong, Sok Kuan

AU - Naina Mohamed, Isa

AU - Mohamed, Norazlina

AU - Kok Yong, Chin

AU - Soelaiman, Ima Nirwana

AU - Shuid, Ahmad Nazrun

PY - 2018/11/1

Y1 - 2018/11/1

N2 - Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

AB - Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.

KW - Anti-inflammatory

KW - Antibacterial

KW - Antioxidant

KW - Collagen

KW - Polyphenols

KW - Skin

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