Wide distribution of virulence genes among Enterococcus faecium and Enterococcus faecalis clinical isolates

Sara Soheili, Sobhan Ghafourian, Zamberi Sekawi, Vasanthakumari Neela, Nourkhoda Sadeghifard, Ramliza Ramli, Rukman Awang Hamat

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Enterococcus, a Gram-positive facultative anaerobic cocci belonging to the lactic acid bacteria of the phylum Firmicutes, is known to be able to resist a wide range of hostile conditions such as different pH levels, high concentration of NaCl (6.5%), and the extended temperatures between 5°C and 65°C. Despite being the third most common nosocomial pathogen, our understanding on its virulence factors is still poorly understood. The current study was aimed to determine the prevalence of different virulence genes in Enterococcus faecalis and Enterococcus faecium. For this purpose, 79 clinical isolates of Malaysian enterococci were evaluated for the presence of virulence genes. pilB, fms8, efaAfm, and sgrA genes are prevalent in all clinical isolates. In conclusion, the pathogenicity of E. faecalis and E. faecium could be associated with different virulence factors and these genes are widely distributed among the enterococcal species.

Original languageEnglish
Article number623174
JournalScientific World Journal
Volume2014
DOIs
Publication statusPublished - 2014

Fingerprint

Enterococcus faecium
Enterococcus faecalis
virulence
Virulence
Genes
gene
Enterococcus
Virulence Factors
pathogenicity
Pathogens
Lactic Acid
Bacteria
pathogen
bacterium
Temperature
distribution
acid
temperature

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Medicine(all)

Cite this

Wide distribution of virulence genes among Enterococcus faecium and Enterococcus faecalis clinical isolates. / Soheili, Sara; Ghafourian, Sobhan; Sekawi, Zamberi; Neela, Vasanthakumari; Sadeghifard, Nourkhoda; Ramli, Ramliza; Hamat, Rukman Awang.

In: Scientific World Journal, Vol. 2014, 623174, 2014.

Research output: Contribution to journalArticle

Soheili, Sara ; Ghafourian, Sobhan ; Sekawi, Zamberi ; Neela, Vasanthakumari ; Sadeghifard, Nourkhoda ; Ramli, Ramliza ; Hamat, Rukman Awang. / Wide distribution of virulence genes among Enterococcus faecium and Enterococcus faecalis clinical isolates. In: Scientific World Journal. 2014 ; Vol. 2014.
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