Weighted analysis of prevalence and risk factors of hepatitis B infection among antenatal mothers in Ipoh

Khadijah Shamsuddin, L. Z. Marmuji

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: Several strategies have been developed to reduce hepatitis B infections. These include antenatal screening, universal immunisation of newborns and immunoglobulin therapy for babies who are at risk. Antenatal screening for hepatitis B is not routinely performed, but all newborns in Malaysia are immunised against hepatitis B. We assessed the prevalence of hepatitis B and the factors associated with it among antenatal mothers in Ipoh. This information is useful in decision-making for future hepatitis B screening programmes for antenatal mothers, allowing for immunoglobulin therapies for newborns if their mother's hepatitis B virus (HBV) status is known. Methods: A cross-sectional study of 1,105 antenatal mothers who attended government health clinics in Ipoh was conducted between July 2008 and October 2008. The participants were asked to complete a self-administered questionnaire, and their hepatitis B surface antigen status was ascertained. Results: A total of 7,172 registered births and 97 HBV carriers were included in the weighted analysis. It revealed that none of the high-risk behaviours explored was significantly associated with HBV infection. Multivariate analysis showed age 35 years and above, multigravida (having two or more pregnancies), a positive history of blood transfusion and a family history of HBV to be signifcant factors associated with HBV infections. Conclusion: The weighted prevalence of HBV infection among antenatal mothers in Ipoh was 1.35 percent. A risk-based screening programme related to past medical and family history may be useful since these two factors are associated with HBV infection.

Original languageEnglish
Pages (from-to)800-805
Number of pages6
JournalSingapore Medical Journal
Volume51
Issue number10
Publication statusPublished - Oct 2010

Fingerprint

Hepatitis B
Hepatitis B virus
Virus Diseases
Infection
Prenatal Diagnosis
Passive Immunization
Medical History Taking
Malaysia
Hepatitis B Surface Antigens
Risk-Taking
Blood Transfusion
Immunization
Decision Making
Multivariate Analysis
Cross-Sectional Studies
Parturition
Pregnancy
Health

Keywords

  • Antenatal screening
  • Hepatitis B
  • Prevalence
  • Risk factors
  • Weighted analysis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Weighted analysis of prevalence and risk factors of hepatitis B infection among antenatal mothers in Ipoh. / Shamsuddin, Khadijah; Marmuji, L. Z.

In: Singapore Medical Journal, Vol. 51, No. 10, 10.2010, p. 800-805.

Research output: Contribution to journalArticle

@article{2224683e2c0b4b5aa659f5f70155155b,
title = "Weighted analysis of prevalence and risk factors of hepatitis B infection among antenatal mothers in Ipoh",
abstract = "Introduction: Several strategies have been developed to reduce hepatitis B infections. These include antenatal screening, universal immunisation of newborns and immunoglobulin therapy for babies who are at risk. Antenatal screening for hepatitis B is not routinely performed, but all newborns in Malaysia are immunised against hepatitis B. We assessed the prevalence of hepatitis B and the factors associated with it among antenatal mothers in Ipoh. This information is useful in decision-making for future hepatitis B screening programmes for antenatal mothers, allowing for immunoglobulin therapies for newborns if their mother's hepatitis B virus (HBV) status is known. Methods: A cross-sectional study of 1,105 antenatal mothers who attended government health clinics in Ipoh was conducted between July 2008 and October 2008. The participants were asked to complete a self-administered questionnaire, and their hepatitis B surface antigen status was ascertained. Results: A total of 7,172 registered births and 97 HBV carriers were included in the weighted analysis. It revealed that none of the high-risk behaviours explored was significantly associated with HBV infection. Multivariate analysis showed age 35 years and above, multigravida (having two or more pregnancies), a positive history of blood transfusion and a family history of HBV to be signifcant factors associated with HBV infections. Conclusion: The weighted prevalence of HBV infection among antenatal mothers in Ipoh was 1.35 percent. A risk-based screening programme related to past medical and family history may be useful since these two factors are associated with HBV infection.",
keywords = "Antenatal screening, Hepatitis B, Prevalence, Risk factors, Weighted analysis",
author = "Khadijah Shamsuddin and Marmuji, {L. Z.}",
year = "2010",
month = "10",
language = "English",
volume = "51",
pages = "800--805",
journal = "Singapore Medical Journal",
issn = "0037-5675",
publisher = "Singapore Medical Association",
number = "10",

}

TY - JOUR

T1 - Weighted analysis of prevalence and risk factors of hepatitis B infection among antenatal mothers in Ipoh

AU - Shamsuddin, Khadijah

AU - Marmuji, L. Z.

PY - 2010/10

Y1 - 2010/10

N2 - Introduction: Several strategies have been developed to reduce hepatitis B infections. These include antenatal screening, universal immunisation of newborns and immunoglobulin therapy for babies who are at risk. Antenatal screening for hepatitis B is not routinely performed, but all newborns in Malaysia are immunised against hepatitis B. We assessed the prevalence of hepatitis B and the factors associated with it among antenatal mothers in Ipoh. This information is useful in decision-making for future hepatitis B screening programmes for antenatal mothers, allowing for immunoglobulin therapies for newborns if their mother's hepatitis B virus (HBV) status is known. Methods: A cross-sectional study of 1,105 antenatal mothers who attended government health clinics in Ipoh was conducted between July 2008 and October 2008. The participants were asked to complete a self-administered questionnaire, and their hepatitis B surface antigen status was ascertained. Results: A total of 7,172 registered births and 97 HBV carriers were included in the weighted analysis. It revealed that none of the high-risk behaviours explored was significantly associated with HBV infection. Multivariate analysis showed age 35 years and above, multigravida (having two or more pregnancies), a positive history of blood transfusion and a family history of HBV to be signifcant factors associated with HBV infections. Conclusion: The weighted prevalence of HBV infection among antenatal mothers in Ipoh was 1.35 percent. A risk-based screening programme related to past medical and family history may be useful since these two factors are associated with HBV infection.

AB - Introduction: Several strategies have been developed to reduce hepatitis B infections. These include antenatal screening, universal immunisation of newborns and immunoglobulin therapy for babies who are at risk. Antenatal screening for hepatitis B is not routinely performed, but all newborns in Malaysia are immunised against hepatitis B. We assessed the prevalence of hepatitis B and the factors associated with it among antenatal mothers in Ipoh. This information is useful in decision-making for future hepatitis B screening programmes for antenatal mothers, allowing for immunoglobulin therapies for newborns if their mother's hepatitis B virus (HBV) status is known. Methods: A cross-sectional study of 1,105 antenatal mothers who attended government health clinics in Ipoh was conducted between July 2008 and October 2008. The participants were asked to complete a self-administered questionnaire, and their hepatitis B surface antigen status was ascertained. Results: A total of 7,172 registered births and 97 HBV carriers were included in the weighted analysis. It revealed that none of the high-risk behaviours explored was significantly associated with HBV infection. Multivariate analysis showed age 35 years and above, multigravida (having two or more pregnancies), a positive history of blood transfusion and a family history of HBV to be signifcant factors associated with HBV infections. Conclusion: The weighted prevalence of HBV infection among antenatal mothers in Ipoh was 1.35 percent. A risk-based screening programme related to past medical and family history may be useful since these two factors are associated with HBV infection.

KW - Antenatal screening

KW - Hepatitis B

KW - Prevalence

KW - Risk factors

KW - Weighted analysis

UR - http://www.scopus.com/inward/record.url?scp=78649420328&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78649420328&partnerID=8YFLogxK

M3 - Article

C2 - 21103816

AN - SCOPUS:78649420328

VL - 51

SP - 800

EP - 805

JO - Singapore Medical Journal

JF - Singapore Medical Journal

SN - 0037-5675

IS - 10

ER -