Vintravenous Ketamine Is As Effective As Midazolam/ Fentanyl For Procedural Sedation and Analgesia in The Emergency Department

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Abstract

The study compared the effectiveness of ketamine and midazolam/fentanyl as procedural sedation and analgesia agents for reduction of fractures and dislocated joints. Forty-one adult patients were enrolled by convenience sampling. They were randomized to receive ketamine or midazolam/fentanyl. Depth of sedation, pain score, procedural outcome and memory of the procedure were documented. The ketamine group had deeper sedation, but there was no statistical difference in other variables between the two groups. Three patients in the midazolam/fentanyl group had oxygen desaturation. More adverse effects were associated with ketamine. Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation.

Original languageEnglish
Pages (from-to)231-233
Number of pages3
JournalMedical Journal of Malaysia
Volume66
Issue number3
Publication statusPublished - Aug 2011

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Midazolam
Ketamine
Fentanyl
Analgesia
Hospital Emergency Service
Deep Sedation
Fracture Fixation
Joints
Oxygen
Pain

Keywords

  • Analgesia
  • Fentanyl
  • Ketamine
  • Midazolam
  • Pain
  • Procedural sedation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Vintravenous Ketamine Is As Effective As Midazolam/ Fentanyl For Procedural Sedation and Analgesia in The Emergency Department",
abstract = "The study compared the effectiveness of ketamine and midazolam/fentanyl as procedural sedation and analgesia agents for reduction of fractures and dislocated joints. Forty-one adult patients were enrolled by convenience sampling. They were randomized to receive ketamine or midazolam/fentanyl. Depth of sedation, pain score, procedural outcome and memory of the procedure were documented. The ketamine group had deeper sedation, but there was no statistical difference in other variables between the two groups. Three patients in the midazolam/fentanyl group had oxygen desaturation. More adverse effects were associated with ketamine. Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation.",
keywords = "Analgesia, Fentanyl, Ketamine, Midazolam, Pain, Procedural sedation",
author = "{Md Jamal}, Shamsuriani and Fathil, {S. M.} and {Mohamad Mahdi}, {Siti Nidzwani} and Ismail, {Ahmad Khaldun} and {Mohd Yatim}, Fadzlon",
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T1 - Vintravenous Ketamine Is As Effective As Midazolam/ Fentanyl For Procedural Sedation and Analgesia in The Emergency Department

AU - Md Jamal, Shamsuriani

AU - Fathil, S. M.

AU - Mohamad Mahdi, Siti Nidzwani

AU - Ismail, Ahmad Khaldun

AU - Mohd Yatim, Fadzlon

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N2 - The study compared the effectiveness of ketamine and midazolam/fentanyl as procedural sedation and analgesia agents for reduction of fractures and dislocated joints. Forty-one adult patients were enrolled by convenience sampling. They were randomized to receive ketamine or midazolam/fentanyl. Depth of sedation, pain score, procedural outcome and memory of the procedure were documented. The ketamine group had deeper sedation, but there was no statistical difference in other variables between the two groups. Three patients in the midazolam/fentanyl group had oxygen desaturation. More adverse effects were associated with ketamine. Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation.

AB - The study compared the effectiveness of ketamine and midazolam/fentanyl as procedural sedation and analgesia agents for reduction of fractures and dislocated joints. Forty-one adult patients were enrolled by convenience sampling. They were randomized to receive ketamine or midazolam/fentanyl. Depth of sedation, pain score, procedural outcome and memory of the procedure were documented. The ketamine group had deeper sedation, but there was no statistical difference in other variables between the two groups. Three patients in the midazolam/fentanyl group had oxygen desaturation. More adverse effects were associated with ketamine. Intravenous ketamine is as effective as midazolam/fentanyl for procedural sedation.

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