Vancomycin resistant enterococci and detection of responsible genes

R. B. Ibrahim, M. Mohamad, Md. Mostafizur Rahman

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: Vancomycin-resistant enterococci (VRE) have been increasing especially in hospital acquired infections. The present study was carried out to determine prevalence of VRE in hospitalized patients and detection of their drug resistance genes by molecular technique. Methodology: The antibiotic susceptibility tests were performed using disk diffusion and E-test. PCR was performed to detect vancomycin resistance genes. Results: Out of 585 enterococcal isolates, 6 (1%) were positive for VRE. 238 isolates (40%) exhibited resistance to high level gentamicin. Among VRE 50% were identified as E. faecium and the entire VRE bacteria posses van A gene. Conclusion: The present study provides the first local data on the prevalence of VRE in Malaysia and would serve as an alert to the clinicians of the emergence of VRE infections and to take appropriate measure to prevent them.

Original languageEnglish
Pages (from-to)784-788
Number of pages5
JournalPakistan Journal of Medical Sciences
Volume27
Issue number4
Publication statusPublished - Oct 2011

Fingerprint

Genes
Vancomycin Resistance
Malaysia
Cross Infection
Vancomycin-Resistant Enterococci
Gentamicins
Drug Resistance
Anti-Bacterial Agents
Bacteria
Polymerase Chain Reaction
Infection

Keywords

  • Antibiotic susceptibility
  • Enterococci
  • Polymerase chain reaction
  • Van A gene
  • Vancomycin resistance

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ibrahim, R. B., Mohamad, M., & Rahman, M. M. (2011). Vancomycin resistant enterococci and detection of responsible genes. Pakistan Journal of Medical Sciences, 27(4), 784-788.

Vancomycin resistant enterococci and detection of responsible genes. / Ibrahim, R. B.; Mohamad, M.; Rahman, Md. Mostafizur.

In: Pakistan Journal of Medical Sciences, Vol. 27, No. 4, 10.2011, p. 784-788.

Research output: Contribution to journalArticle

Ibrahim, RB, Mohamad, M & Rahman, MM 2011, 'Vancomycin resistant enterococci and detection of responsible genes', Pakistan Journal of Medical Sciences, vol. 27, no. 4, pp. 784-788.
Ibrahim, R. B. ; Mohamad, M. ; Rahman, Md. Mostafizur. / Vancomycin resistant enterococci and detection of responsible genes. In: Pakistan Journal of Medical Sciences. 2011 ; Vol. 27, No. 4. pp. 784-788.
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