Validation study of the Malay version of the Myasthenia Gravis Quality of Life (MGQOL)15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires

Alif Adlan Mohd Thabit, Nor Azman Rosli, Hana Maizuliana Solehan, Zahariah Pilus, Maskanah Mohammad Lotfie, Ramesh Sahathevan, Norlinah Mohamed Ibrahim, Hui Jan Tan, Wan Nur Nafisah Wan Yahya, Hazlina Mahadzir, Shahrul Azmin Md. Rani, Zhe Kang Law, Rabani Remli

Research output: Contribution to journalArticle

Abstract

Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to measure patients’ perception of MG-related dysfunction. This study aims to validate the translated Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using the cross cultural adaptation process, both questionnaires were translated into Malay language. Two sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this study comprising predominantly females compared to males (71% vs 29%) and Malays compared to non-Malays (60% vs 40%). The mean age was 52.5 years; with most of the patients in the 60-69 years old category (37%).The Spearman’s correlation coefficient was 0.987 for MGQOL-15 Malay version and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and MGADL Malay version are reliable and valid instruments for the measurement of quality of life in MG patients in the local setting.

Original languageEnglish
Pages (from-to)33-39
Number of pages7
JournalNeurology Asia
Volume21
Issue number1
Publication statusPublished - 1 Mar 2016

Fingerprint

Validation Studies
Myasthenia Gravis
Activities of Daily Living
Quality of Life
Surveys and Questionnaires
Neuromuscular Diseases

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Validation study of the Malay version of the Myasthenia Gravis Quality of Life (MGQOL)15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires. / Thabit, Alif Adlan Mohd; Rosli, Nor Azman; Solehan, Hana Maizuliana; Pilus, Zahariah; Lotfie, Maskanah Mohammad; Sahathevan, Ramesh; Mohamed Ibrahim, Norlinah; Tan, Hui Jan; Wan Yahya, Wan Nur Nafisah; Mahadzir, Hazlina; Md. Rani, Shahrul Azmin; Law, Zhe Kang; Remli, Rabani.

In: Neurology Asia, Vol. 21, No. 1, 01.03.2016, p. 33-39.

Research output: Contribution to journalArticle

@article{c3673a3411b743498982f1201405a871,
title = "Validation study of the Malay version of the Myasthenia Gravis Quality of Life (MGQOL)15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires",
abstract = "Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to measure patients’ perception of MG-related dysfunction. This study aims to validate the translated Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using the cross cultural adaptation process, both questionnaires were translated into Malay language. Two sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this study comprising predominantly females compared to males (71{\%} vs 29{\%}) and Malays compared to non-Malays (60{\%} vs 40{\%}). The mean age was 52.5 years; with most of the patients in the 60-69 years old category (37{\%}).The Spearman’s correlation coefficient was 0.987 for MGQOL-15 Malay version and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and MGADL Malay version are reliable and valid instruments for the measurement of quality of life in MG patients in the local setting.",
author = "Thabit, {Alif Adlan Mohd} and Rosli, {Nor Azman} and Solehan, {Hana Maizuliana} and Zahariah Pilus and Lotfie, {Maskanah Mohammad} and Ramesh Sahathevan and {Mohamed Ibrahim}, Norlinah and Tan, {Hui Jan} and {Wan Yahya}, {Wan Nur Nafisah} and Hazlina Mahadzir and {Md. Rani}, {Shahrul Azmin} and Law, {Zhe Kang} and Rabani Remli",
year = "2016",
month = "3",
day = "1",
language = "English",
volume = "21",
pages = "33--39",
journal = "Neurology Asia",
issn = "1823-6138",
publisher = "ASEAN Neurological Association",
number = "1",

}

TY - JOUR

T1 - Validation study of the Malay version of the Myasthenia Gravis Quality of Life (MGQOL)15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires

AU - Thabit, Alif Adlan Mohd

AU - Rosli, Nor Azman

AU - Solehan, Hana Maizuliana

AU - Pilus, Zahariah

AU - Lotfie, Maskanah Mohammad

AU - Sahathevan, Ramesh

AU - Mohamed Ibrahim, Norlinah

AU - Tan, Hui Jan

AU - Wan Yahya, Wan Nur Nafisah

AU - Mahadzir, Hazlina

AU - Md. Rani, Shahrul Azmin

AU - Law, Zhe Kang

AU - Remli, Rabani

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to measure patients’ perception of MG-related dysfunction. This study aims to validate the translated Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using the cross cultural adaptation process, both questionnaires were translated into Malay language. Two sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this study comprising predominantly females compared to males (71% vs 29%) and Malays compared to non-Malays (60% vs 40%). The mean age was 52.5 years; with most of the patients in the 60-69 years old category (37%).The Spearman’s correlation coefficient was 0.987 for MGQOL-15 Malay version and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and MGADL Malay version are reliable and valid instruments for the measurement of quality of life in MG patients in the local setting.

AB - Myasthenia gravis (MG) is an immune mediated neuromuscular disease causing fatiguability, which can influence quality of life (QOL). MG disease status can be established with Myasthenia Gravis Quality of Life (MGQOL) 15 and Myasthenia Gravis Activities of Daily Living (MGADL) questionnaires to measure patients’ perception of MG-related dysfunction. This study aims to validate the translated Malay versions of the MGQOL15 and MGADL for use in Malay-speaking MG patients. By using the cross cultural adaptation process, both questionnaires were translated into Malay language. Two sets of MGQOL15 Malay version and MGADL Malay version were distributed to MG patients during their routine follow-up to be filled up one week apart. A total of 38 patients were recruited during this study comprising predominantly females compared to males (71% vs 29%) and Malays compared to non-Malays (60% vs 40%). The mean age was 52.5 years; with most of the patients in the 60-69 years old category (37%).The Spearman’s correlation coefficient was 0.987 for MGQOL-15 Malay version and 0.976 for MGADL Malay version, while the internal consistency for MGQOL15 Malay version was 0.952-0.957, and 0.677-0.694 for MGADL Malay version. The MGQOL15 Malay version and MGADL Malay version are reliable and valid instruments for the measurement of quality of life in MG patients in the local setting.

UR - http://www.scopus.com/inward/record.url?scp=84962433268&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962433268&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84962433268

VL - 21

SP - 33

EP - 39

JO - Neurology Asia

JF - Neurology Asia

SN - 1823-6138

IS - 1

ER -