Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children

A. Liu, N. M. Byrne, G. Ma, L. Nasreddine, T. P. Trinidad, K. Kijboonchoo, M. N. Ismail, M. Kagawa, Bee Koon Poh, A. P. Hills

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background/Objectives: To develop and cross-validate bioelectrical impedance analysis (BIA) prediction equations of total body water (TBW) and fat-free mass (FFM) for Asian pre-pubertal children from China, Lebanon, Malaysia, Philippines and Thailand. Subjects/Methods: Height, weight, age, gender, resistance and reactance measured by BIA were collected from 948 Asian children (492 boys and 456 girls) aged 8-10 years from the five countries. The deuterium dilution technique was used as the criterion method for the estimation of TBW and FFM. The BIA equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach. Results: The BIA prediction equation for the estimation of TBW was as follows: TBW=0.231 × height 2/resistance+ 0.066 × height+0.188 × weight+0.128 × age+0.500 × sex-0.316 × Thais-4.574 (R 2=88.0%, root mean square error (RMSE)=1.3 kg), and for the estimation of FFM was as follows: FFM=0.299 × height 2/ resistance+0.086 × height+0.245 × weight+0.260 × age+0.901 × sex-0.415 × ethnicity (Thai ethnicity = 1, others = 0)-6.952 (R 2 88.3%, RMSE=1.7 kg). No significant difference between measured and predicted values for the whole cross-validation sample was found. However, the prediction equation for estimation of TBW/FFM tended to overestimate TBW/FFM at lower levels whereas underestimate at higher levels of TBW/FFM. Accuracy of the general equation for TBW and FFM was also valid at each body mass index category.Conclusions:Ethnicity influences the relationship between BIA and body composition in Asian pre-pubertal children. The newly developed BIA prediction equations are valid for use in Asian pre-pubertal children.

Original languageEnglish
Pages (from-to)1321-1327
Number of pages7
JournalEuropean Journal of Clinical Nutrition
Volume65
Issue number12
DOIs
Publication statusPublished - Dec 2011

Fingerprint

Indicator Dilution Techniques
Body Water
Deuterium
Electric Impedance
Fats
Adipose Tissue
Weights and Measures
Lebanon
Philippines
Malaysia
Thailand
Body Composition
China
Body Mass Index
Regression Analysis

Keywords

  • Asia
  • bioelectrical impedance analysis
  • body composition
  • children
  • fat-free mass
  • total body water

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children. / Liu, A.; Byrne, N. M.; Ma, G.; Nasreddine, L.; Trinidad, T. P.; Kijboonchoo, K.; Ismail, M. N.; Kagawa, M.; Poh, Bee Koon; Hills, A. P.

In: European Journal of Clinical Nutrition, Vol. 65, No. 12, 12.2011, p. 1321-1327.

Research output: Contribution to journalArticle

Liu, A, Byrne, NM, Ma, G, Nasreddine, L, Trinidad, TP, Kijboonchoo, K, Ismail, MN, Kagawa, M, Poh, BK & Hills, AP 2011, 'Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children', European Journal of Clinical Nutrition, vol. 65, no. 12, pp. 1321-1327. https://doi.org/10.1038/ejcn.2011.122
Liu, A. ; Byrne, N. M. ; Ma, G. ; Nasreddine, L. ; Trinidad, T. P. ; Kijboonchoo, K. ; Ismail, M. N. ; Kagawa, M. ; Poh, Bee Koon ; Hills, A. P. / Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children. In: European Journal of Clinical Nutrition. 2011 ; Vol. 65, No. 12. pp. 1321-1327.
@article{db8b638be78c43809445da4e8f7c96e3,
title = "Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children",
abstract = "Background/Objectives: To develop and cross-validate bioelectrical impedance analysis (BIA) prediction equations of total body water (TBW) and fat-free mass (FFM) for Asian pre-pubertal children from China, Lebanon, Malaysia, Philippines and Thailand. Subjects/Methods: Height, weight, age, gender, resistance and reactance measured by BIA were collected from 948 Asian children (492 boys and 456 girls) aged 8-10 years from the five countries. The deuterium dilution technique was used as the criterion method for the estimation of TBW and FFM. The BIA equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach. Results: The BIA prediction equation for the estimation of TBW was as follows: TBW=0.231 × height 2/resistance+ 0.066 × height+0.188 × weight+0.128 × age+0.500 × sex-0.316 × Thais-4.574 (R 2=88.0{\%}, root mean square error (RMSE)=1.3 kg), and for the estimation of FFM was as follows: FFM=0.299 × height 2/ resistance+0.086 × height+0.245 × weight+0.260 × age+0.901 × sex-0.415 × ethnicity (Thai ethnicity = 1, others = 0)-6.952 (R 2 88.3{\%}, RMSE=1.7 kg). No significant difference between measured and predicted values for the whole cross-validation sample was found. However, the prediction equation for estimation of TBW/FFM tended to overestimate TBW/FFM at lower levels whereas underestimate at higher levels of TBW/FFM. Accuracy of the general equation for TBW and FFM was also valid at each body mass index category.Conclusions:Ethnicity influences the relationship between BIA and body composition in Asian pre-pubertal children. The newly developed BIA prediction equations are valid for use in Asian pre-pubertal children.",
keywords = "Asia, bioelectrical impedance analysis, body composition, children, fat-free mass, total body water",
author = "A. Liu and Byrne, {N. M.} and G. Ma and L. Nasreddine and Trinidad, {T. P.} and K. Kijboonchoo and Ismail, {M. N.} and M. Kagawa and Poh, {Bee Koon} and Hills, {A. P.}",
year = "2011",
month = "12",
doi = "10.1038/ejcn.2011.122",
language = "English",
volume = "65",
pages = "1321--1327",
journal = "European Journal of Clinical Nutrition",
issn = "0954-3007",
publisher = "Nature Publishing Group",
number = "12",

}

TY - JOUR

T1 - Validation of bioelectrical impedance analysis for total body water assessment against the deuterium dilution technique in Asian children

AU - Liu, A.

AU - Byrne, N. M.

AU - Ma, G.

AU - Nasreddine, L.

AU - Trinidad, T. P.

AU - Kijboonchoo, K.

AU - Ismail, M. N.

AU - Kagawa, M.

AU - Poh, Bee Koon

AU - Hills, A. P.

PY - 2011/12

Y1 - 2011/12

N2 - Background/Objectives: To develop and cross-validate bioelectrical impedance analysis (BIA) prediction equations of total body water (TBW) and fat-free mass (FFM) for Asian pre-pubertal children from China, Lebanon, Malaysia, Philippines and Thailand. Subjects/Methods: Height, weight, age, gender, resistance and reactance measured by BIA were collected from 948 Asian children (492 boys and 456 girls) aged 8-10 years from the five countries. The deuterium dilution technique was used as the criterion method for the estimation of TBW and FFM. The BIA equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach. Results: The BIA prediction equation for the estimation of TBW was as follows: TBW=0.231 × height 2/resistance+ 0.066 × height+0.188 × weight+0.128 × age+0.500 × sex-0.316 × Thais-4.574 (R 2=88.0%, root mean square error (RMSE)=1.3 kg), and for the estimation of FFM was as follows: FFM=0.299 × height 2/ resistance+0.086 × height+0.245 × weight+0.260 × age+0.901 × sex-0.415 × ethnicity (Thai ethnicity = 1, others = 0)-6.952 (R 2 88.3%, RMSE=1.7 kg). No significant difference between measured and predicted values for the whole cross-validation sample was found. However, the prediction equation for estimation of TBW/FFM tended to overestimate TBW/FFM at lower levels whereas underestimate at higher levels of TBW/FFM. Accuracy of the general equation for TBW and FFM was also valid at each body mass index category.Conclusions:Ethnicity influences the relationship between BIA and body composition in Asian pre-pubertal children. The newly developed BIA prediction equations are valid for use in Asian pre-pubertal children.

AB - Background/Objectives: To develop and cross-validate bioelectrical impedance analysis (BIA) prediction equations of total body water (TBW) and fat-free mass (FFM) for Asian pre-pubertal children from China, Lebanon, Malaysia, Philippines and Thailand. Subjects/Methods: Height, weight, age, gender, resistance and reactance measured by BIA were collected from 948 Asian children (492 boys and 456 girls) aged 8-10 years from the five countries. The deuterium dilution technique was used as the criterion method for the estimation of TBW and FFM. The BIA equations were developed using stepwise multiple regression analysis and cross-validated using the Bland-Altman approach. Results: The BIA prediction equation for the estimation of TBW was as follows: TBW=0.231 × height 2/resistance+ 0.066 × height+0.188 × weight+0.128 × age+0.500 × sex-0.316 × Thais-4.574 (R 2=88.0%, root mean square error (RMSE)=1.3 kg), and for the estimation of FFM was as follows: FFM=0.299 × height 2/ resistance+0.086 × height+0.245 × weight+0.260 × age+0.901 × sex-0.415 × ethnicity (Thai ethnicity = 1, others = 0)-6.952 (R 2 88.3%, RMSE=1.7 kg). No significant difference between measured and predicted values for the whole cross-validation sample was found. However, the prediction equation for estimation of TBW/FFM tended to overestimate TBW/FFM at lower levels whereas underestimate at higher levels of TBW/FFM. Accuracy of the general equation for TBW and FFM was also valid at each body mass index category.Conclusions:Ethnicity influences the relationship between BIA and body composition in Asian pre-pubertal children. The newly developed BIA prediction equations are valid for use in Asian pre-pubertal children.

KW - Asia

KW - bioelectrical impedance analysis

KW - body composition

KW - children

KW - fat-free mass

KW - total body water

UR - http://www.scopus.com/inward/record.url?scp=82955232973&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82955232973&partnerID=8YFLogxK

U2 - 10.1038/ejcn.2011.122

DO - 10.1038/ejcn.2011.122

M3 - Article

C2 - 21731041

AN - SCOPUS:82955232973

VL - 65

SP - 1321

EP - 1327

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

SN - 0954-3007

IS - 12

ER -