Penggunaan pelarut eutektik dalam (DES) sebagai porogen dalam fabrikasi turus kapilari monolitik polimerik

Translated title of the contribution: Utilization of deep eutectic solvent (DES) as porogen in the fabrication of polymeric monolithic capillary column

Nabilah Suhaili, Lee Wah Lim, Takeuchi Toyohide, Rizafizah Othaman

Research output: Contribution to journalArticle

Abstract

Deep eutectic solvents (DESs) from quaternary salts and hydrogen bond donors (HBDs) formation are widely known as an alternative for ionic liquid (IL) and commonly introduced in the synthesis of mesoporous materials. In this study, four types of choline chloride (ChCl) based DESs were prepared, and their utilization as porogens in fabricating methacrylate-based monolithic capillary columns was investigated. The selected DESs were prepared from different HBDs, including from organic acid (methacrylic acid MAA), alcohol (ethylene glycol EG), organic base (urea), and also combination of alcohol and organic base (EG and urea). This study found that the type of HBDs used have a crucial impact on the pore formation, and the results showed that DES A (ChCl:urea:EG) could effectively improve the structure of the monoliths and enhanced chromatographic separation for non-polar polycyclic aromatic hydrocarbons (PAHs). For repeatability evaluation using DES A in separation analysis, five PAHs achieved relative standard deviations (RSDs) of retention time in the range of 1.39 – 1.91%. Due to the lowest backpressure value (0.4 MPa) compared to other types of DESs, DES A that contained both HBDs from organic base and alcohol is believed to inherit both feature characteristics such as formation of through-pore and mesopore skeletal in monoliths column. A novel green stationary phase for separation of PAHs compounds was successfully synthesized using simple one-step polymerization with low cost and toxicity of DESs mixture as porogenic solvents instead of using traditional organic solvents.

Original languageMalay
Pages (from-to)667-676
Number of pages10
JournalMalaysian Journal of Analytical Sciences
Volume23
Issue number4
DOIs
Publication statusPublished - 1 Aug 2019

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Eutectics
Fabrication
Polycyclic Aromatic Hydrocarbons
Hydrogen bonds
Urea
Alcohols
Choline
Ionic Liquids
Mesoporous materials
Ethylene Glycol
Methacrylates
Organic acids
Organic solvents
Toxicity
Salts
Polymerization
Costs

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Penggunaan pelarut eutektik dalam (DES) sebagai porogen dalam fabrikasi turus kapilari monolitik polimerik. / Suhaili, Nabilah; Lim, Lee Wah; Toyohide, Takeuchi; Othaman, Rizafizah.

In: Malaysian Journal of Analytical Sciences, Vol. 23, No. 4, 01.08.2019, p. 667-676.

Research output: Contribution to journalArticle

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AB - Deep eutectic solvents (DESs) from quaternary salts and hydrogen bond donors (HBDs) formation are widely known as an alternative for ionic liquid (IL) and commonly introduced in the synthesis of mesoporous materials. In this study, four types of choline chloride (ChCl) based DESs were prepared, and their utilization as porogens in fabricating methacrylate-based monolithic capillary columns was investigated. The selected DESs were prepared from different HBDs, including from organic acid (methacrylic acid MAA), alcohol (ethylene glycol EG), organic base (urea), and also combination of alcohol and organic base (EG and urea). This study found that the type of HBDs used have a crucial impact on the pore formation, and the results showed that DES A (ChCl:urea:EG) could effectively improve the structure of the monoliths and enhanced chromatographic separation for non-polar polycyclic aromatic hydrocarbons (PAHs). For repeatability evaluation using DES A in separation analysis, five PAHs achieved relative standard deviations (RSDs) of retention time in the range of 1.39 – 1.91%. Due to the lowest backpressure value (0.4 MPa) compared to other types of DESs, DES A that contained both HBDs from organic base and alcohol is believed to inherit both feature characteristics such as formation of through-pore and mesopore skeletal in monoliths column. A novel green stationary phase for separation of PAHs compounds was successfully synthesized using simple one-step polymerization with low cost and toxicity of DESs mixture as porogenic solvents instead of using traditional organic solvents.

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