Using systems biology to solve the riddle of recalcitrant tropical plants

Normah Mohd. Noor

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Systems biology is an interdisciplinary approach that focuses on complex biological systems. It is aimed at explaining and understanding the properties and behavior of the biological systems especially the dynamics aspect of network behavior. This requires the integration of experimental and computational research. The systems biology approach has the ability to obtain, integrate and analyze complex data from multiple experimental sources using interdisciplinary tools, such as 'omics' technology and computational biology platforms. This approach has been used to study the biosynthetic pathways of secondary metabolites in plants and microbes, which will facilitate the fundamental components in secondary metabolite production. Hence various manipulations could be carried out to increase the production of metabolites of interest. A similar approach could be used to study recalcitrance in plants. Recalcitrant tropical plants are known to be difficult to manipulate in culture (recalcitrant in culture or to micropropagation) and are a problem to conserve, as they are sensitive to desiccation and low temperature. Attempts to cryopreserve these species have met with unsuccessful results. The knowledge on fundamental aspects of these recalcitrant characteristics is limited; hence, the development of cryopreservation protocols is hindered and the reasons for failures remain unknown or only partially understood. Systems biology may provide a fundamental approach to improve the current understanding of recalcitrant species. Future efforts should focus on the generation of new data (genomics, proteomics, transcriptomics, and metabolomics) on different conditions, and then the focus should be on data integration to investigate and evaluate the metabolic and regulatory conditions (or models) of recalcitrance. Integration of this data will lead to the discovery of potential factors that are useful in solving the recalcitrant seed storage problems. Research using this approach has started in various groups but an international consortium is needed to put this enormous amount of data together at a faster rate.

Original languageEnglish
Title of host publicationActa Horticulturae
PublisherInternational Society for Horticultural Science
Pages211-218
Number of pages8
Volume1039
ISBN (Print)9789462610279
Publication statusPublished - 22 Jun 2014

Publication series

NameActa Horticulturae
Volume1039
ISSN (Print)05677572

Fingerprint

Biological Sciences
secondary metabolites
seed storage
metabolomics
micropropagation
transcriptomics
bioinformatics
proteomics
cryopreservation
biochemical pathways
metabolites
microorganisms
genomics
temperature
recalcitrant species
recalcitrant seeds

Keywords

  • Desiccation sensitive
  • Genomics
  • Low temperature sensitive
  • Metabolomics
  • Proteomics

ASJC Scopus subject areas

  • Horticulture

Cite this

Mohd. Noor, N. (2014). Using systems biology to solve the riddle of recalcitrant tropical plants. In Acta Horticulturae (Vol. 1039, pp. 211-218). (Acta Horticulturae; Vol. 1039). International Society for Horticultural Science.

Using systems biology to solve the riddle of recalcitrant tropical plants. / Mohd. Noor, Normah.

Acta Horticulturae. Vol. 1039 International Society for Horticultural Science, 2014. p. 211-218 (Acta Horticulturae; Vol. 1039).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mohd. Noor, N 2014, Using systems biology to solve the riddle of recalcitrant tropical plants. in Acta Horticulturae. vol. 1039, Acta Horticulturae, vol. 1039, International Society for Horticultural Science, pp. 211-218.
Mohd. Noor N. Using systems biology to solve the riddle of recalcitrant tropical plants. In Acta Horticulturae. Vol. 1039. International Society for Horticultural Science. 2014. p. 211-218. (Acta Horticulturae).
Mohd. Noor, Normah. / Using systems biology to solve the riddle of recalcitrant tropical plants. Acta Horticulturae. Vol. 1039 International Society for Horticultural Science, 2014. pp. 211-218 (Acta Horticulturae).
@inproceedings{d05a3a1ce911433c8c7a051ea30cb9a6,
title = "Using systems biology to solve the riddle of recalcitrant tropical plants",
abstract = "Systems biology is an interdisciplinary approach that focuses on complex biological systems. It is aimed at explaining and understanding the properties and behavior of the biological systems especially the dynamics aspect of network behavior. This requires the integration of experimental and computational research. The systems biology approach has the ability to obtain, integrate and analyze complex data from multiple experimental sources using interdisciplinary tools, such as 'omics' technology and computational biology platforms. This approach has been used to study the biosynthetic pathways of secondary metabolites in plants and microbes, which will facilitate the fundamental components in secondary metabolite production. Hence various manipulations could be carried out to increase the production of metabolites of interest. A similar approach could be used to study recalcitrance in plants. Recalcitrant tropical plants are known to be difficult to manipulate in culture (recalcitrant in culture or to micropropagation) and are a problem to conserve, as they are sensitive to desiccation and low temperature. Attempts to cryopreserve these species have met with unsuccessful results. The knowledge on fundamental aspects of these recalcitrant characteristics is limited; hence, the development of cryopreservation protocols is hindered and the reasons for failures remain unknown or only partially understood. Systems biology may provide a fundamental approach to improve the current understanding of recalcitrant species. Future efforts should focus on the generation of new data (genomics, proteomics, transcriptomics, and metabolomics) on different conditions, and then the focus should be on data integration to investigate and evaluate the metabolic and regulatory conditions (or models) of recalcitrance. Integration of this data will lead to the discovery of potential factors that are useful in solving the recalcitrant seed storage problems. Research using this approach has started in various groups but an international consortium is needed to put this enormous amount of data together at a faster rate.",
keywords = "Desiccation sensitive, Genomics, Low temperature sensitive, Metabolomics, Proteomics",
author = "{Mohd. Noor}, Normah",
year = "2014",
month = "6",
day = "22",
language = "English",
isbn = "9789462610279",
volume = "1039",
series = "Acta Horticulturae",
publisher = "International Society for Horticultural Science",
pages = "211--218",
booktitle = "Acta Horticulturae",

}

TY - GEN

T1 - Using systems biology to solve the riddle of recalcitrant tropical plants

AU - Mohd. Noor, Normah

PY - 2014/6/22

Y1 - 2014/6/22

N2 - Systems biology is an interdisciplinary approach that focuses on complex biological systems. It is aimed at explaining and understanding the properties and behavior of the biological systems especially the dynamics aspect of network behavior. This requires the integration of experimental and computational research. The systems biology approach has the ability to obtain, integrate and analyze complex data from multiple experimental sources using interdisciplinary tools, such as 'omics' technology and computational biology platforms. This approach has been used to study the biosynthetic pathways of secondary metabolites in plants and microbes, which will facilitate the fundamental components in secondary metabolite production. Hence various manipulations could be carried out to increase the production of metabolites of interest. A similar approach could be used to study recalcitrance in plants. Recalcitrant tropical plants are known to be difficult to manipulate in culture (recalcitrant in culture or to micropropagation) and are a problem to conserve, as they are sensitive to desiccation and low temperature. Attempts to cryopreserve these species have met with unsuccessful results. The knowledge on fundamental aspects of these recalcitrant characteristics is limited; hence, the development of cryopreservation protocols is hindered and the reasons for failures remain unknown or only partially understood. Systems biology may provide a fundamental approach to improve the current understanding of recalcitrant species. Future efforts should focus on the generation of new data (genomics, proteomics, transcriptomics, and metabolomics) on different conditions, and then the focus should be on data integration to investigate and evaluate the metabolic and regulatory conditions (or models) of recalcitrance. Integration of this data will lead to the discovery of potential factors that are useful in solving the recalcitrant seed storage problems. Research using this approach has started in various groups but an international consortium is needed to put this enormous amount of data together at a faster rate.

AB - Systems biology is an interdisciplinary approach that focuses on complex biological systems. It is aimed at explaining and understanding the properties and behavior of the biological systems especially the dynamics aspect of network behavior. This requires the integration of experimental and computational research. The systems biology approach has the ability to obtain, integrate and analyze complex data from multiple experimental sources using interdisciplinary tools, such as 'omics' technology and computational biology platforms. This approach has been used to study the biosynthetic pathways of secondary metabolites in plants and microbes, which will facilitate the fundamental components in secondary metabolite production. Hence various manipulations could be carried out to increase the production of metabolites of interest. A similar approach could be used to study recalcitrance in plants. Recalcitrant tropical plants are known to be difficult to manipulate in culture (recalcitrant in culture or to micropropagation) and are a problem to conserve, as they are sensitive to desiccation and low temperature. Attempts to cryopreserve these species have met with unsuccessful results. The knowledge on fundamental aspects of these recalcitrant characteristics is limited; hence, the development of cryopreservation protocols is hindered and the reasons for failures remain unknown or only partially understood. Systems biology may provide a fundamental approach to improve the current understanding of recalcitrant species. Future efforts should focus on the generation of new data (genomics, proteomics, transcriptomics, and metabolomics) on different conditions, and then the focus should be on data integration to investigate and evaluate the metabolic and regulatory conditions (or models) of recalcitrance. Integration of this data will lead to the discovery of potential factors that are useful in solving the recalcitrant seed storage problems. Research using this approach has started in various groups but an international consortium is needed to put this enormous amount of data together at a faster rate.

KW - Desiccation sensitive

KW - Genomics

KW - Low temperature sensitive

KW - Metabolomics

KW - Proteomics

UR - http://www.scopus.com/inward/record.url?scp=84904989291&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84904989291&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:84904989291

SN - 9789462610279

VL - 1039

T3 - Acta Horticulturae

SP - 211

EP - 218

BT - Acta Horticulturae

PB - International Society for Horticultural Science

ER -