Usage of allogeneic single layered tissue engineered skin enhance wound treatment in sheep.

P. R Mohd Adha, Chua Kien Hui, Mazlyzam Abdul Latif, K. C. Low, B. S. Aminuddin, Ruszymah Idrus

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A major factor limiting survival following extensive thermal injury is insufficient availability of donor sites to provide enough skin for the required grafting procedures. Limitation of autologous grafting promotes the usage of allograft skin substitutes to promote wound healing. Here, we investigated the wound healing potential of allograft single layered tissue engineered skin which comprises of either keratinocytes (SLTES-K) or fibroblast (SLTES-F) with fibrin as the delivery system. Results from gross and microscopic evaluation showed our single layered tissue engineered skin constructed with keratinocytes or fibroblast after gamma radiation with the dosage of 2Gy could serve as allograft for the treatment of skin loss.

Original languageEnglish
Pages (from-to)30-31
Number of pages2
JournalThe Medical journal of Malaysia
Volume63 Suppl A
Publication statusPublished - Jul 2008

Fingerprint

Allografts
Sheep
Keratinocytes
Wound Healing
Skin
Wounds and Injuries
Fibroblasts
Artificial Skin
Radiation Dosage
Skin Transplantation
Gamma Rays
Fibrin
Therapeutics
Hot Temperature

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Usage of allogeneic single layered tissue engineered skin enhance wound treatment in sheep. / Adha, P. R Mohd; Kien Hui, Chua; Abdul Latif, Mazlyzam; Low, K. C.; Aminuddin, B. S.; Idrus, Ruszymah.

In: The Medical journal of Malaysia, Vol. 63 Suppl A, 07.2008, p. 30-31.

Research output: Contribution to journalArticle

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