Undercorrection of myopia enhances rather than inhibits myopia progression

Kahmeng Chung, Norhani Mohidin, Daniel J. O'Leary

    Research output: Contribution to journalArticle

    144 Citations (Scopus)

    Abstract

    The effect of myopic defocus on myopia progression was assessed in a two-year prospective study on 94 myopes aged 9-14 years, randomly allocated to an undercorrected group or a fully corrected control group. The 47 experimental subjects were blurred by approximately +0.75 D (blurring VA to 6/12), while the controls were fully corrected. Undercorrection produced more rapid myopia progression and axial elongation (ANOVA, F(1,374)=14.32, p<0.01). Contrary to animal studies, myopic defocus speeds up myopia development in already myopic humans. Myopia could be caused by a failure to detect the direction of defocus rather than by a mechanism exhibiting a zero-point error.

    Original languageEnglish
    Pages (from-to)2555-2559
    Number of pages5
    JournalVision Research
    Volume42
    Issue number22
    DOIs
    Publication statusPublished - Oct 2002

    Fingerprint

    Myopia
    Analysis of Variance
    Prospective Studies
    Control Groups

    Keywords

    • Emmetropization
    • Myopia
    • Refractive error

    ASJC Scopus subject areas

    • Ophthalmology
    • Sensory Systems

    Cite this

    Undercorrection of myopia enhances rather than inhibits myopia progression. / Chung, Kahmeng; Mohidin, Norhani; O'Leary, Daniel J.

    In: Vision Research, Vol. 42, No. 22, 10.2002, p. 2555-2559.

    Research output: Contribution to journalArticle

    Chung, Kahmeng ; Mohidin, Norhani ; O'Leary, Daniel J. / Undercorrection of myopia enhances rather than inhibits myopia progression. In: Vision Research. 2002 ; Vol. 42, No. 22. pp. 2555-2559.
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