Two new methyl chanofruticosinates from Kopsia flavida blume

Khairana Husain, Ibrahim Jantan, Ikram M. Said, Norio Aimi, Hiromitsu Takayama

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1- decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N1-decarbomethoxy-14, 15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1- decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.

Original languageEnglish
Pages (from-to)63-67
Number of pages5
JournalJournal of Asian Natural Products Research
Volume5
Issue number1
DOIs
Publication statusPublished - Mar 2003

Fingerprint

Indole Alkaloids
indole alkaloids
musculoskeletal system
spectral analysis
Nuclear magnetic resonance
leaves
methodology

Keywords

  • Apocynaceae
  • Indole alkaloids
  • Kopsia fiavida Blume
  • Methyl chanofruticosinate skeletal system

ASJC Scopus subject areas

  • Plant Science
  • Chemistry (miscellaneous)
  • Drug Discovery
  • Organic Chemistry
  • Pharmacology

Cite this

Two new methyl chanofruticosinates from Kopsia flavida blume. / Husain, Khairana; Jantan, Ibrahim; Said, Ikram M.; Aimi, Norio; Takayama, Hiromitsu.

In: Journal of Asian Natural Products Research, Vol. 5, No. 1, 03.2003, p. 63-67.

Research output: Contribution to journalArticle

Husain, Khairana ; Jantan, Ibrahim ; Said, Ikram M. ; Aimi, Norio ; Takayama, Hiromitsu. / Two new methyl chanofruticosinates from Kopsia flavida blume. In: Journal of Asian Natural Products Research. 2003 ; Vol. 5, No. 1. pp. 63-67.
@article{d059f718d0d74c74b58dce443fa5d022,
title = "Two new methyl chanofruticosinates from Kopsia flavida blume",
abstract = "Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1- decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N1-decarbomethoxy-14, 15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1- decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.",
keywords = "Apocynaceae, Indole alkaloids, Kopsia fiavida Blume, Methyl chanofruticosinate skeletal system",
author = "Khairana Husain and Ibrahim Jantan and Said, {Ikram M.} and Norio Aimi and Hiromitsu Takayama",
year = "2003",
month = "3",
doi = "10.1080/1028602031000080487",
language = "English",
volume = "5",
pages = "63--67",
journal = "Journal of Asian Natural Products Research",
issn = "1028-6020",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

TY - JOUR

T1 - Two new methyl chanofruticosinates from Kopsia flavida blume

AU - Husain, Khairana

AU - Jantan, Ibrahim

AU - Said, Ikram M.

AU - Aimi, Norio

AU - Takayama, Hiromitsu

PY - 2003/3

Y1 - 2003/3

N2 - Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1- decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N1-decarbomethoxy-14, 15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1- decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.

AB - Two new indole alkaloids with the methyl chanofruticosinate skeletal system viz., methyl 3-oxo-12-methoxy-N1- decarbomethoxy-14,15-didehydrochanofruticosinate (1) and methyl 3-oxo-11,12-methylenedioxy-N1-decarbomethoxy-14, 15-didehydrochanofruticosinate (2), together with four known compounds, methyl 12-methoxy-N1- decarbomethoxychanofruticosinate, methyl 12-methoxychanofruticosinate, methyl 11,12-dimethoxychanofruticosinate and methyl 11,12-methylenedioxy-N1-decarbomethoxychanofruticosinate, were isolated in continuing studies on the leaves of Kopsia flavida Blume. The structures of the new indole alkaloids were assigned by NMR spectral data using various 2D-techniques.

KW - Apocynaceae

KW - Indole alkaloids

KW - Kopsia fiavida Blume

KW - Methyl chanofruticosinate skeletal system

UR - http://www.scopus.com/inward/record.url?scp=0037355615&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037355615&partnerID=8YFLogxK

U2 - 10.1080/1028602031000080487

DO - 10.1080/1028602031000080487

M3 - Article

C2 - 12608641

AN - SCOPUS:0037355615

VL - 5

SP - 63

EP - 67

JO - Journal of Asian Natural Products Research

JF - Journal of Asian Natural Products Research

SN - 1028-6020

IS - 1

ER -