Treatment of multiple-level tracheobronchial stenosis secondary to endobronchial tuberculosis using bronchoscopic balloon dilatation with topical mitomycin-C

Mohamed Faisal, Hafaruzi Harun, Hassan Tidi Maharani, Rea Ban Yu-Lin, Sanjay H. Chotirmall, Jamalul Azizi Abdul Rahaman

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Tracheobronchial stenosis is a known complication of endobronchial tuberculosis. Despite antituberculous and steroid therapy, the development of bronchial stenosis is usually irreversible and requires airway patency to be restored by either bronchoscopic or surgical interventions. We report the use of balloon dilatation and topical mitomycin-C to successful restore airway patency. Case presentation: We present a 24-year old lady with previous pulmonary tuberculosis and laryngeal tuberculosis in 2007 and 2013 respectively who presented with worsening dyspnoea and stridor. She had total left lung collapse with stenosis of both the upper trachea and left main bronchus. She underwent successful bronchoscopic balloon and manual rigid tube dilatation with topical mitomycin-C application over the stenotic tracheal segment. A second bronchoscopic intervention was performed after 20weeks for the left main bronchus stenosis with serial balloon dilatation and topical mitomycin-C application. These interventions led to significant clinical and radiographic improvements. Conclusion: This case highlights that balloon dilatation and topical mitomycin-C application should be considered in selected patients with tracheobronchial stenosis following endobronchial tuberculosis, avoiding airway stenting and invasive surgical intervention.

Original languageEnglish
Article number53
JournalBMC Pulmonary Medicine
Volume16
Issue number1
DOIs
Publication statusPublished - 14 Apr 2016

Fingerprint

Mitomycin
Dilatation
Pathologic Constriction
Tuberculosis
Bronchi
Laryngeal Tuberculosis
Therapeutics
Pulmonary Atelectasis
Respiratory Sounds
Trachea
Pulmonary Tuberculosis
Dyspnea
Steroids

Keywords

  • Bronchoscopic intervention
  • Case report
  • Endobronchial tuberculosis
  • Mitomycin-C

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Treatment of multiple-level tracheobronchial stenosis secondary to endobronchial tuberculosis using bronchoscopic balloon dilatation with topical mitomycin-C. / Faisal, Mohamed; Harun, Hafaruzi; Tidi Maharani, Hassan; Ban Yu-Lin, Rea; Chotirmall, Sanjay H.; Abdul Rahaman, Jamalul Azizi.

In: BMC Pulmonary Medicine, Vol. 16, No. 1, 53, 14.04.2016.

Research output: Contribution to journalArticle

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