Transposable elements adaptive role in genome plasticity, pathogenicity and evolution in fungal phytopathogens

Nurhani Mat Razali, Boon Huat Cheah, Kalaivani K. Nadarajah

Research output: Contribution to journalReview article

Abstract

Transposable elements (TEs) are agents of genetic variability in phytopathogens as they are a source of adaptive evolution through genome diversification. Although many studies have uncovered information on TEs, the exact mechanism behind TE-induced changes within the genome remains poorly understood. Furthermore, convergent trends towards bigger genomes, emergence of novel genes and gain or loss of genes implicate a TE-regulated genome plasticity of fungal phytopathogens. TEs are able to alter gene expression by revamping the cis-regulatory elements or recruiting epigenetic control. Recent findings show that TEs recruit epigenetic control on the expression of effector genes as part of the coordinated infection strategy. In addition to genome plasticity and diversity, fungal pathogenicity is an area of economic concern. A survey of TE distribution suggests that their proximity to pathogenicity genes TEs may act as sites for emergence of novel pathogenicity factors via nucleotide changes and expansion or reduction of the gene family. Through a systematic survey of literature, we were able to conclude that the role of TEs in fungi is wide: ranging from genome plasticity, pathogenicity to adaptive behavior in evolution. This review also identifies the gaps in knowledge that requires further elucidation for a better understanding of TEs’ contribution to genome architecture and versatility.

Original languageEnglish
Article number3597
JournalInternational journal of molecular sciences
Volume20
Issue number14
DOIs
Publication statusPublished - 2 Jul 2019

Fingerprint

DNA Transposable Elements
genome
plastic properties
Plasticity
Virulence
Genes
Genome
genes
Epigenomics
effectors
fungi
gene expression
nucleotides
Fungal Genome
infectious diseases
versatility
Gene Expression
economics
proximity
Psychological Adaptation

Keywords

  • Evolution
  • Genome plasticity
  • Pathogenicity
  • Phytopathogen
  • Transposable elements

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

Transposable elements adaptive role in genome plasticity, pathogenicity and evolution in fungal phytopathogens. / Razali, Nurhani Mat; Cheah, Boon Huat; K. Nadarajah, Kalaivani.

In: International journal of molecular sciences, Vol. 20, No. 14, 3597, 02.07.2019.

Research output: Contribution to journalReview article

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