Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide

Izumi C. Mori, Carlos R. Arias-Barreiro, Apostolos Koutsaftis, Atsushi Ogo, Tomonori Kawano, Kazuharu Yoshizuka, Salmaan H. Inayat-Hussain, Isao Aoyama

    Research output: Contribution to journalArticle

    24 Citations (Scopus)

    Abstract

    The aquatic ecotoxicity of chemicals involved in the manufacturing process of thin film transistor liquid crystal displays was assessed with a battery of four selected acute toxicity bioassays. We focused on tetramethylammonium hydroxide (TMAH, CAS No. 75-59-2), a widely utilized etchant. The toxicity of TMAH was low when tested in the 72h-algal growth inhibition test (Pseudokirchneriellia subcapitata, EC50=360mgL-1) and the Microtox® test (Vibrio fischeri, IC50=6.4gL-1). In contrast, the 24h-microcrustacean immobilization and the 96h-fish mortality tests showed relatively higher toxicity (Daphnia magna, EC50=32mgL-1 and Oryzias latipes, LC50=154mgL-1). Isobologram and mixture toxicity index analyses revealed apparent synergism of the mixture of TMAH and potassium iodide when examined with the D. magna immobilization test. The synergistic action was unique to iodide over other halide salts i.e. fluoride, chloride and bromide. Quaternary ammonium ions with longer alkyl chains such as tetraethylammonium and tetrabutylammonium were more toxic than TMAH in the D. magna immobilization test.

    Original languageEnglish
    Pages (from-to)299-304
    Number of pages6
    JournalChemosphere
    Volume120
    DOIs
    Publication statusPublished - 1 Feb 2015

    Fingerprint

    Potassium iodide
    Aquatic organisms
    Potassium Iodide
    Aquatic Organisms
    iodide
    aquatic organism
    Immobilization
    hydroxide
    Toxicity
    potassium
    toxicity
    immobilization
    Aliivibrio fischeri
    Oryzias
    Daphnia
    Liquid Crystals
    Tetraethylammonium
    Poisons
    Iodides
    Bromides

    Keywords

    • Aquatic toxicity
    • D. magna
    • Potassium iodide
    • Semiconductor wastewater
    • Synergism
    • Tetramethylammonium hydroxide

    ASJC Scopus subject areas

    • Environmental Chemistry
    • Chemistry(all)

    Cite this

    Mori, I. C., Arias-Barreiro, C. R., Koutsaftis, A., Ogo, A., Kawano, T., Yoshizuka, K., ... Aoyama, I. (2015). Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide. Chemosphere, 120, 299-304. https://doi.org/10.1016/j.chemosphere.2014.07.011

    Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide. / Mori, Izumi C.; Arias-Barreiro, Carlos R.; Koutsaftis, Apostolos; Ogo, Atsushi; Kawano, Tomonori; Yoshizuka, Kazuharu; Inayat-Hussain, Salmaan H.; Aoyama, Isao.

    In: Chemosphere, Vol. 120, 01.02.2015, p. 299-304.

    Research output: Contribution to journalArticle

    Mori, IC, Arias-Barreiro, CR, Koutsaftis, A, Ogo, A, Kawano, T, Yoshizuka, K, Inayat-Hussain, SH & Aoyama, I 2015, 'Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide', Chemosphere, vol. 120, pp. 299-304. https://doi.org/10.1016/j.chemosphere.2014.07.011
    Mori, Izumi C. ; Arias-Barreiro, Carlos R. ; Koutsaftis, Apostolos ; Ogo, Atsushi ; Kawano, Tomonori ; Yoshizuka, Kazuharu ; Inayat-Hussain, Salmaan H. ; Aoyama, Isao. / Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide. In: Chemosphere. 2015 ; Vol. 120. pp. 299-304.
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