Therapeutic effects of connective tissue manipulation on wound healing and bacterial colonization count among patients with diabetic foot ulcer

Leonard Henry Joseph, Aatit Paungmali, John Dixon, Liz Holey, Amaramalar Selvi Naicker, Ohnmar Htwe

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This study investigated the therapeutic effects of connective tissue manipulation (CTM) in diabetic foot ulcer (DFU). A total of 20 participants (10 in CTM group and 10 in conventional treatment group (CG)) with DFU underwent the conventional DFU treatment. In addition, the CTM group received CTM twice per week for 6 weeks. The percentage wound area reduction (PWAR) and bacterial colonization count (BCC) in log10 colony-forming units (CFU) per ml wound fluid was evaluated at baseline and six weeks. Results showed a significant change in PWAR in CTM (p <0.05, t = 3.82, Df = 9, CI L = 0.98 U = 3.81) and CG (p <0.05, t = 2.97, Df = 9,CI L = 0.26 U = 1.98). Mean reduction of BCC showed a significant reduction (p <0.05), with percentage of BCC reduction higher in CTM group (6.45%) than CG (3.55%). The findings suggest CTM as an effective adjunct therapy for DFU to enhance conventional treatments.

Original languageEnglish
JournalJournal of Bodywork and Movement Therapies
DOIs
Publication statusAccepted/In press - 15 Oct 2015

Fingerprint

Diabetic Foot
Bacterial Load
Therapeutic Uses
Connective Tissue
Wound Healing
Wounds and Injuries
Therapeutics
Stem Cells

Keywords

  • Connective tissue manipulation
  • Diabetes
  • Physiotherapy
  • Rehabilitation
  • Ulcer

ASJC Scopus subject areas

  • Complementary and alternative medicine
  • Rehabilitation
  • Complementary and Manual Therapy
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

@article{55309bc4338e4d39a5e8b769b96d2a84,
title = "Therapeutic effects of connective tissue manipulation on wound healing and bacterial colonization count among patients with diabetic foot ulcer",
abstract = "This study investigated the therapeutic effects of connective tissue manipulation (CTM) in diabetic foot ulcer (DFU). A total of 20 participants (10 in CTM group and 10 in conventional treatment group (CG)) with DFU underwent the conventional DFU treatment. In addition, the CTM group received CTM twice per week for 6 weeks. The percentage wound area reduction (PWAR) and bacterial colonization count (BCC) in log10 colony-forming units (CFU) per ml wound fluid was evaluated at baseline and six weeks. Results showed a significant change in PWAR in CTM (p <0.05, t = 3.82, Df = 9, CI L = 0.98 U = 3.81) and CG (p <0.05, t = 2.97, Df = 9,CI L = 0.26 U = 1.98). Mean reduction of BCC showed a significant reduction (p <0.05), with percentage of BCC reduction higher in CTM group (6.45{\%}) than CG (3.55{\%}). The findings suggest CTM as an effective adjunct therapy for DFU to enhance conventional treatments.",
keywords = "Connective tissue manipulation, Diabetes, Physiotherapy, Rehabilitation, Ulcer",
author = "Joseph, {Leonard Henry} and Aatit Paungmali and John Dixon and Liz Holey and {Selvi Naicker}, Amaramalar and Ohnmar Htwe",
year = "2015",
month = "10",
day = "15",
doi = "10.1016/j.jbmt.2016.01.010",
language = "English",
journal = "Journal of Bodywork and Movement Therapies",
issn = "1360-8592",
publisher = "Churchill Livingstone",

}

TY - JOUR

T1 - Therapeutic effects of connective tissue manipulation on wound healing and bacterial colonization count among patients with diabetic foot ulcer

AU - Joseph, Leonard Henry

AU - Paungmali, Aatit

AU - Dixon, John

AU - Holey, Liz

AU - Selvi Naicker, Amaramalar

AU - Htwe, Ohnmar

PY - 2015/10/15

Y1 - 2015/10/15

N2 - This study investigated the therapeutic effects of connective tissue manipulation (CTM) in diabetic foot ulcer (DFU). A total of 20 participants (10 in CTM group and 10 in conventional treatment group (CG)) with DFU underwent the conventional DFU treatment. In addition, the CTM group received CTM twice per week for 6 weeks. The percentage wound area reduction (PWAR) and bacterial colonization count (BCC) in log10 colony-forming units (CFU) per ml wound fluid was evaluated at baseline and six weeks. Results showed a significant change in PWAR in CTM (p <0.05, t = 3.82, Df = 9, CI L = 0.98 U = 3.81) and CG (p <0.05, t = 2.97, Df = 9,CI L = 0.26 U = 1.98). Mean reduction of BCC showed a significant reduction (p <0.05), with percentage of BCC reduction higher in CTM group (6.45%) than CG (3.55%). The findings suggest CTM as an effective adjunct therapy for DFU to enhance conventional treatments.

AB - This study investigated the therapeutic effects of connective tissue manipulation (CTM) in diabetic foot ulcer (DFU). A total of 20 participants (10 in CTM group and 10 in conventional treatment group (CG)) with DFU underwent the conventional DFU treatment. In addition, the CTM group received CTM twice per week for 6 weeks. The percentage wound area reduction (PWAR) and bacterial colonization count (BCC) in log10 colony-forming units (CFU) per ml wound fluid was evaluated at baseline and six weeks. Results showed a significant change in PWAR in CTM (p <0.05, t = 3.82, Df = 9, CI L = 0.98 U = 3.81) and CG (p <0.05, t = 2.97, Df = 9,CI L = 0.26 U = 1.98). Mean reduction of BCC showed a significant reduction (p <0.05), with percentage of BCC reduction higher in CTM group (6.45%) than CG (3.55%). The findings suggest CTM as an effective adjunct therapy for DFU to enhance conventional treatments.

KW - Connective tissue manipulation

KW - Diabetes

KW - Physiotherapy

KW - Rehabilitation

KW - Ulcer

UR - http://www.scopus.com/inward/record.url?scp=84959419925&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959419925&partnerID=8YFLogxK

U2 - 10.1016/j.jbmt.2016.01.010

DO - 10.1016/j.jbmt.2016.01.010

M3 - Article

JO - Journal of Bodywork and Movement Therapies

JF - Journal of Bodywork and Movement Therapies

SN - 1360-8592

ER -