Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits

Fathy M. Awad, Zainal Abidin Abu Hasan, Abdinasir Yusuf Osman, Nazlina Ibrahim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic extract (CEE) compared to those from the negative control group. Similarly, there was also haematologically significant difference (p<0.05) where low mean levels of packed cell volume (PCV) was observed in Groups 1-4 respectively. In contrast, there was no statistically significant difference in almost all investigated parameters between positive control and treatment groups of animals. In conclusion, both CEE of A. herba-alba and Berenil® showed relatively a parasitaemia and normal haematological values in infected rabbits, thereby confirming their antiparasitic properties.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages177-179
Number of pages3
Volume1571
DOIs
Publication statusPublished - 2013
Event2013 UKM Faculty of Science and Technology Post-Graduate Colloquium - Selangor
Duration: 3 Jul 20134 Jul 2013

Other

Other2013 UKM Faculty of Science and Technology Post-Graduate Colloquium
CitySelangor
Period3/7/134/7/13

Fingerprint

rabbits
animal models
infectious diseases
animals
cells

Keywords

  • Artemisia herba alba
  • Parasitaemia
  • Rabbits
  • Trypanosoma evansi

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Awad, F. M., Hasan, Z. A. A., Osman, A. Y., & Ibrahim, N. (2013). Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits. In AIP Conference Proceedings (Vol. 1571, pp. 177-179) https://doi.org/10.1063/1.4858650

Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits. / Awad, Fathy M.; Hasan, Zainal Abidin Abu; Osman, Abdinasir Yusuf; Ibrahim, Nazlina.

AIP Conference Proceedings. Vol. 1571 2013. p. 177-179.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Awad, FM, Hasan, ZAA, Osman, AY & Ibrahim, N 2013, Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits. in AIP Conference Proceedings. vol. 1571, pp. 177-179, 2013 UKM Faculty of Science and Technology Post-Graduate Colloquium, Selangor, 3/7/13. https://doi.org/10.1063/1.4858650
Awad, Fathy M. ; Hasan, Zainal Abidin Abu ; Osman, Abdinasir Yusuf ; Ibrahim, Nazlina. / Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits. AIP Conference Proceedings. Vol. 1571 2013. pp. 177-179
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