The Use of Engineered Bilayered Skin (MyDermTM) in the Management of Massive Skin Defect in Grade III Gustilo-Anderson Open Fracture

Nor Hazla Mohamed Haflah, Min Hwei Ng, Mohd Heikal Mohd Yunus, Amaramalar Selvee Naicker, Ohnmar Htwe, Muhammad Fahmi, Mohamad Fikeri Ishak, Wan Tai Seet, Khairul Anuar Khairoji, Manira Maarof, Kien Hui Chua, Sharen Aini Shamsuddin, Ruszymah Idrus

Research output: Research - peer-reviewArticle

Abstract

Open fracture Gustilo-Anderson grade IIIC is associated with higher risk of infection and problems with soft tissue coverage. Various methods have been used for soft tissue coverage in open fractures with large skin defect. We report a case of a patient who had grade IIIC open fracture of the tibia with posterior tibial artery injury. The patient underwent external fixation and reduction. Because of potential compartment syndrome after vascular repair, fasciotomy of the posterior compartment was performed. This wound, however, became infected and because of further debridement, gave rise to a large skin defect. A tissue engineered skin construct, MyDermTM was employed to cover this large defect. Complete wound closure was achieved 35 days postimplantation. The patient then underwent plating of the tibia for nonunion with no adverse effect to the grafted site. The tibia eventually healed 5 months postplating, and the cosmetic appearance of the newly formed skin was satisfactory.

LanguageEnglish
Pages212-216
Number of pages5
JournalInternational Journal of Lower Extremity Wounds
Volume16
Issue number3
DOIs
StatePublished - 1 Sep 2017

Fingerprint

Open Fractures
Skin
Tibia
Wounds and Injuries
Tibial Arteries
Compartment Syndromes
Debridement
Cosmetics
Blood Vessels
Infection
Fasciotomy

Keywords

  • fasciotomy
  • massive skin defect
  • open fracture
  • skin graft
  • tissue engineering

ASJC Scopus subject areas

  • Surgery

Cite this

The Use of Engineered Bilayered Skin (MyDermTM) in the Management of Massive Skin Defect in Grade III Gustilo-Anderson Open Fracture. / Mohamed Haflah, Nor Hazla; Ng, Min Hwei; Mohd Yunus, Mohd Heikal; Naicker, Amaramalar Selvee; Htwe, Ohnmar; Fahmi, Muhammad; Ishak, Mohamad Fikeri; Seet, Wan Tai; Khairoji, Khairul Anuar; Maarof, Manira; Chua, Kien Hui; Shamsuddin, Sharen Aini; Idrus, Ruszymah.

In: International Journal of Lower Extremity Wounds, Vol. 16, No. 3, 01.09.2017, p. 212-216.

Research output: Research - peer-reviewArticle

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