The use of dexmedetomidine for refractory agitation in substance abuse patient

Raha Abdul Rahman, Muhd Helmi Azmi, Nadia Hanom Ishak, Norsidah Abdul Manap, Jaafar Md Zain

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Psychomotor disturbance in Intensive Care Unit (ICU) continues to be a challenging issue in view of its various ranges of predisposing factors and this includes withdrawal from chronic substance abuse. A combination of opioids, benzodiazepines and antipsychotics are often used to treat such neurochemical disturbances. We report a case of 43 year-old man with 10 years history of substance abuse who presented with acute opioids intoxication. He required mechanical ventilation but exhibited significant agitation in the ICU. The conventional combination of midazolam and morphine, and later propofol infusion failed to control his agitations following admission. However, his symptoms improved and he was extubated within the first 24 hours of stay after dexmedetomidine infusion.

Original languageEnglish
Pages (from-to)59-60
Number of pages2
JournalCritical Care and Shock
Volume13
Issue number2
Publication statusPublished - May 2010

Fingerprint

Dexmedetomidine
Opioid Analgesics
Substance-Related Disorders
Intensive Care Units
Midazolam
Propofol
Benzodiazepines
Artificial Respiration
Causality
Morphine
Antipsychotic Agents

Keywords

  • Agitation
  • Dexmedetomidine
  • Substance abuse
  • Withdrawal

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

The use of dexmedetomidine for refractory agitation in substance abuse patient. / Abdul Rahman, Raha; Azmi, Muhd Helmi; Ishak, Nadia Hanom; Abdul Manap, Norsidah; Md Zain, Jaafar.

In: Critical Care and Shock, Vol. 13, No. 2, 05.2010, p. 59-60.

Research output: Contribution to journalArticle

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