The use of bone marrow stem cells for bone tissue engineering.

Min Hwei Ng, B. S. Aminuddin, K. K. Tan, G. H. Tan, Sabarul Afian Mokhtar, Ruszymah Idrus

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Bone marrow stem cells (BMSC), known for its multipotency to differentiate into various mesenchymal cells such as chodrocyte, osteoblasts, adipocytes, etc, have been actively applied in tissue engineering. BMSC have been successfully isolated from bone marrow aspirate and bone marrow scraping from patients of various ages (13-56 years) with as little as 2ml to 5ml aspirate. BMSC isolated from our laboratory showed the presence of a heterogenous population that showed varying prevalence of surface antigens and the presence of telomerase activity albeit weak. Upon osteogenic induction, alkaline phosphatase activity and mineralization activity were observed.

Original languageEnglish
Pages (from-to)41-42
Number of pages2
JournalThe Medical journal of Malaysia
Volume59 Suppl B
Publication statusPublished - May 2004

Fingerprint

Tissue Engineering
Bone Marrow Cells
Stem Cells
Bone and Bones
Bone Marrow
Telomerase
Surface Antigens
Osteoblasts
Adipocytes
Alkaline Phosphatase
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The use of bone marrow stem cells for bone tissue engineering. / Ng, Min Hwei; Aminuddin, B. S.; Tan, K. K.; Tan, G. H.; Mokhtar, Sabarul Afian; Idrus, Ruszymah.

In: The Medical journal of Malaysia, Vol. 59 Suppl B, 05.2004, p. 41-42.

Research output: Contribution to journalArticle

@article{5e4f20548f0b45ae8b463a23c11474aa,
title = "The use of bone marrow stem cells for bone tissue engineering.",
abstract = "Bone marrow stem cells (BMSC), known for its multipotency to differentiate into various mesenchymal cells such as chodrocyte, osteoblasts, adipocytes, etc, have been actively applied in tissue engineering. BMSC have been successfully isolated from bone marrow aspirate and bone marrow scraping from patients of various ages (13-56 years) with as little as 2ml to 5ml aspirate. BMSC isolated from our laboratory showed the presence of a heterogenous population that showed varying prevalence of surface antigens and the presence of telomerase activity albeit weak. Upon osteogenic induction, alkaline phosphatase activity and mineralization activity were observed.",
author = "Ng, {Min Hwei} and Aminuddin, {B. S.} and Tan, {K. K.} and Tan, {G. H.} and Mokhtar, {Sabarul Afian} and Ruszymah Idrus",
year = "2004",
month = "5",
language = "English",
volume = "59 Suppl B",
pages = "41--42",
journal = "Medical Journal of Malaysia",
issn = "0300-5283",
publisher = "Malaysian Medical Association",

}

TY - JOUR

T1 - The use of bone marrow stem cells for bone tissue engineering.

AU - Ng, Min Hwei

AU - Aminuddin, B. S.

AU - Tan, K. K.

AU - Tan, G. H.

AU - Mokhtar, Sabarul Afian

AU - Idrus, Ruszymah

PY - 2004/5

Y1 - 2004/5

N2 - Bone marrow stem cells (BMSC), known for its multipotency to differentiate into various mesenchymal cells such as chodrocyte, osteoblasts, adipocytes, etc, have been actively applied in tissue engineering. BMSC have been successfully isolated from bone marrow aspirate and bone marrow scraping from patients of various ages (13-56 years) with as little as 2ml to 5ml aspirate. BMSC isolated from our laboratory showed the presence of a heterogenous population that showed varying prevalence of surface antigens and the presence of telomerase activity albeit weak. Upon osteogenic induction, alkaline phosphatase activity and mineralization activity were observed.

AB - Bone marrow stem cells (BMSC), known for its multipotency to differentiate into various mesenchymal cells such as chodrocyte, osteoblasts, adipocytes, etc, have been actively applied in tissue engineering. BMSC have been successfully isolated from bone marrow aspirate and bone marrow scraping from patients of various ages (13-56 years) with as little as 2ml to 5ml aspirate. BMSC isolated from our laboratory showed the presence of a heterogenous population that showed varying prevalence of surface antigens and the presence of telomerase activity albeit weak. Upon osteogenic induction, alkaline phosphatase activity and mineralization activity were observed.

UR - http://www.scopus.com/inward/record.url?scp=16544362494&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16544362494&partnerID=8YFLogxK

M3 - Article

C2 - 15468809

AN - SCOPUS:16544362494

VL - 59 Suppl B

SP - 41

EP - 42

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

SN - 0300-5283

ER -