The treatment of primary nocturnal enuresis in Malaysia

Kanaheswari P. Yoganathan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To determine treatment outcomes in Malaysian children with primary nocturnal enuresis using both non-pharmacological methods and oral desmopressin. Data was collected prospectively from children aged 6-18 years who were referred to the Hospital UKM Enuresis Clinic. Treatment was given to those with a baseline wetting frequency of at least six wet nights/ 14 nights. Three modalities were offered: fluid management, reward system and oral desmopressin. Response was recorded as partial (≥ 50% reduction in WN from baseline) or full (completely dry). Seventy-one healthy children completed 12 weeks of therapy. Twenty-three children (32.4%) responded to non-pharmacological methods alone (4 full and 19 partial). Another 37 children (51.2%) responded to oral desmopressin (32 to 0.2mg, 4 to 0.4mg and 1 to 0.6mg). Thirty-two percent became dry whilst on therapy. The mean wetting frequency during treatment was significantly reduced (p<0.01) compared to the baseline mean for both the non-pharmacological group and the desmopressin group. Discontinuation of desmopressin after 12 weeks increased the wetting frequency but this was still significantly lower than at baseline (p<0.01). No adverse events were recorded. Treatment of primary nocturnal enuresis in Malaysian children is both effective and well tolerated using fluid management strategies, reward systems and oral desmopressin.

Original languageEnglish
Pages (from-to)608-615
Number of pages8
JournalMedical Journal of Malaysia
Volume61
Issue number5
Publication statusPublished - Dec 2006

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Nocturnal Enuresis
Deamino Arginine Vasopressin
Malaysia
Reward
Therapeutics
Enuresis

Keywords

  • Desmopressin
  • Non-pharmacological methods
  • Primary nocturnal enuresis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The treatment of primary nocturnal enuresis in Malaysia. / P. Yoganathan, Kanaheswari.

In: Medical Journal of Malaysia, Vol. 61, No. 5, 12.2006, p. 608-615.

Research output: Contribution to journalArticle

P. Yoganathan, K 2006, 'The treatment of primary nocturnal enuresis in Malaysia', Medical Journal of Malaysia, vol. 61, no. 5, pp. 608-615.
P. Yoganathan, Kanaheswari. / The treatment of primary nocturnal enuresis in Malaysia. In: Medical Journal of Malaysia. 2006 ; Vol. 61, No. 5. pp. 608-615.
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