The treatment of neck lymphangioma with intralesional injection of bleomycin.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

We report our experience with intralesional injection of bleomycin in the treatment of neck lymphangioma. From May 1995 to April 1998, 11 patients aged between 6 to 22 months were treated with intralesional bleomycin injection. Ultrasonography and computed tomography were used to assess and select the cases suitable for sclerotherapy. Patients with lesions encasing the internal jugular vein and the carotid artery were chosen. With the patient under sedation and using ultrasound guidance, the cysts were aspirated and bleomycin was injected at a dose of 0.5 mg/kg body weight. The number of procedures varied from 1 to 4 over a period of 8 months to 1 year. Patients were initially followed-up 3 monthly, then 6 monthly and subsequently yearly. In 4 patients, the neck mass was no longer visible (excellent response). In 5 patients, the neck mass had reduced to a size (more than 50% reduction) that was cosmetically acceptable (good response). There were 2 failures (poor response). There were no complications. Our results suggest that intralesional injection of bleomycin can be effectively used to treat selected cases of neck lymphangiomas.

Original languageEnglish
Pages (from-to)478-481
Number of pages4
JournalMedical Journal of Malaysia
Volume54
Issue number4
Publication statusPublished - Dec 1999

Fingerprint

Intralesional Injections
Lymphangioma
Bleomycin
Neck
Therapeutics
Sclerotherapy
Jugular Veins
Carotid Arteries
Cysts
Ultrasonography
Tomography
Body Weight

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The treatment of neck lymphangioma with intralesional injection of bleomycin. / Zulfiqar, M. A.; Abdullah Mahdy, Zaleha; Syed Zakaria, Syed Zulkifli; Amin, T.

In: Medical Journal of Malaysia, Vol. 54, No. 4, 12.1999, p. 478-481.

Research output: Contribution to journalArticle

@article{3dca1b696d304a4ab56204b958178f18,
title = "The treatment of neck lymphangioma with intralesional injection of bleomycin.",
abstract = "We report our experience with intralesional injection of bleomycin in the treatment of neck lymphangioma. From May 1995 to April 1998, 11 patients aged between 6 to 22 months were treated with intralesional bleomycin injection. Ultrasonography and computed tomography were used to assess and select the cases suitable for sclerotherapy. Patients with lesions encasing the internal jugular vein and the carotid artery were chosen. With the patient under sedation and using ultrasound guidance, the cysts were aspirated and bleomycin was injected at a dose of 0.5 mg/kg body weight. The number of procedures varied from 1 to 4 over a period of 8 months to 1 year. Patients were initially followed-up 3 monthly, then 6 monthly and subsequently yearly. In 4 patients, the neck mass was no longer visible (excellent response). In 5 patients, the neck mass had reduced to a size (more than 50{\%} reduction) that was cosmetically acceptable (good response). There were 2 failures (poor response). There were no complications. Our results suggest that intralesional injection of bleomycin can be effectively used to treat selected cases of neck lymphangiomas.",
author = "Zulfiqar, {M. A.} and {Abdullah Mahdy}, Zaleha and {Syed Zakaria}, {Syed Zulkifli} and T. Amin",
year = "1999",
month = "12",
language = "English",
volume = "54",
pages = "478--481",
journal = "Medical Journal of Malaysia",
issn = "0300-5283",
publisher = "Malaysian Medical Association",
number = "4",

}

TY - JOUR

T1 - The treatment of neck lymphangioma with intralesional injection of bleomycin.

AU - Zulfiqar, M. A.

AU - Abdullah Mahdy, Zaleha

AU - Syed Zakaria, Syed Zulkifli

AU - Amin, T.

PY - 1999/12

Y1 - 1999/12

N2 - We report our experience with intralesional injection of bleomycin in the treatment of neck lymphangioma. From May 1995 to April 1998, 11 patients aged between 6 to 22 months were treated with intralesional bleomycin injection. Ultrasonography and computed tomography were used to assess and select the cases suitable for sclerotherapy. Patients with lesions encasing the internal jugular vein and the carotid artery were chosen. With the patient under sedation and using ultrasound guidance, the cysts were aspirated and bleomycin was injected at a dose of 0.5 mg/kg body weight. The number of procedures varied from 1 to 4 over a period of 8 months to 1 year. Patients were initially followed-up 3 monthly, then 6 monthly and subsequently yearly. In 4 patients, the neck mass was no longer visible (excellent response). In 5 patients, the neck mass had reduced to a size (more than 50% reduction) that was cosmetically acceptable (good response). There were 2 failures (poor response). There were no complications. Our results suggest that intralesional injection of bleomycin can be effectively used to treat selected cases of neck lymphangiomas.

AB - We report our experience with intralesional injection of bleomycin in the treatment of neck lymphangioma. From May 1995 to April 1998, 11 patients aged between 6 to 22 months were treated with intralesional bleomycin injection. Ultrasonography and computed tomography were used to assess and select the cases suitable for sclerotherapy. Patients with lesions encasing the internal jugular vein and the carotid artery were chosen. With the patient under sedation and using ultrasound guidance, the cysts were aspirated and bleomycin was injected at a dose of 0.5 mg/kg body weight. The number of procedures varied from 1 to 4 over a period of 8 months to 1 year. Patients were initially followed-up 3 monthly, then 6 monthly and subsequently yearly. In 4 patients, the neck mass was no longer visible (excellent response). In 5 patients, the neck mass had reduced to a size (more than 50% reduction) that was cosmetically acceptable (good response). There were 2 failures (poor response). There were no complications. Our results suggest that intralesional injection of bleomycin can be effectively used to treat selected cases of neck lymphangiomas.

UR - http://www.scopus.com/inward/record.url?scp=0033289453&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033289453&partnerID=8YFLogxK

M3 - Article

C2 - 11072465

AN - SCOPUS:0033289453

VL - 54

SP - 478

EP - 481

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

SN - 0300-5283

IS - 4

ER -