The surgical treatment of adrenal diseases

F. A. Meah, T. Abdullah, A. Y. Jasmi, A. N. Hisham, T. T. Tan, B. A K Khalid, A. Tahir

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Between January 1978 to December 1993, 130 cases of adrenal diseases were diagnosed and surgically treated at the National University of Malaysia. They were 58 cases (44.6%) of Conn's syndrome, 40 cases (30.7%) of Cushing's syndrome, 20 cases (15.3%) of phaeochromocytoma and 12 cases (9.2%) of adrenocortical carcinoma (ACC). The commonest cause of Conn's syndrome was an adenoma (96.5%) which affected the left gland four times more than the right gland. Cushing's syndrome was caused by adrenocortical adenoma (32.5%), diffuse bilateral adrenal hyperplasia (40.0%), pigmented macronodular hyperplasia (20.0%) and adrenal carcinoma (7.5%). Twenty-five percent of the phaeochromocytomas were extraadrenal in origin arising mainly from the abdominal sympathetic chain. More than 50% of ACCs were non-functioning tumours. Fifty percent of the patients with ACC had inoperable tumours. The prognosis was poor even with adjuvant chemoradiotherapy. The main surgical approach was the anterior transabdominal route. There was no operative mortality or mobidity in all operated cases.

    Original languageEnglish
    Pages (from-to)251-254
    Number of pages4
    JournalAnnals of the Academy of Medicine Singapore
    Volume25
    Issue number2
    Publication statusPublished - Mar 1996

    Fingerprint

    Adrenocortical Carcinoma
    Hyperaldosteronism
    Cushing Syndrome
    Pheochromocytoma
    Hyperplasia
    Adjuvant Chemoradiotherapy
    Adrenocortical Adenoma
    Malaysia
    Adenoma
    Neoplasms
    Carcinoma
    Mortality
    Therapeutics

    Keywords

    • Adrenal gland
    • Adrenalectomy
    • Conn's syndrome
    • Cushing's syndrome
    • Phaeochromocytoma

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    Meah, F. A., Abdullah, T., Jasmi, A. Y., Hisham, A. N., Tan, T. T., Khalid, B. A. K., & Tahir, A. (1996). The surgical treatment of adrenal diseases. Annals of the Academy of Medicine Singapore, 25(2), 251-254.

    The surgical treatment of adrenal diseases. / Meah, F. A.; Abdullah, T.; Jasmi, A. Y.; Hisham, A. N.; Tan, T. T.; Khalid, B. A K; Tahir, A.

    In: Annals of the Academy of Medicine Singapore, Vol. 25, No. 2, 03.1996, p. 251-254.

    Research output: Contribution to journalArticle

    Meah, FA, Abdullah, T, Jasmi, AY, Hisham, AN, Tan, TT, Khalid, BAK & Tahir, A 1996, 'The surgical treatment of adrenal diseases', Annals of the Academy of Medicine Singapore, vol. 25, no. 2, pp. 251-254.
    Meah FA, Abdullah T, Jasmi AY, Hisham AN, Tan TT, Khalid BAK et al. The surgical treatment of adrenal diseases. Annals of the Academy of Medicine Singapore. 1996 Mar;25(2):251-254.
    Meah, F. A. ; Abdullah, T. ; Jasmi, A. Y. ; Hisham, A. N. ; Tan, T. T. ; Khalid, B. A K ; Tahir, A. / The surgical treatment of adrenal diseases. In: Annals of the Academy of Medicine Singapore. 1996 ; Vol. 25, No. 2. pp. 251-254.
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