The significance of using pooled human serum in human articular cartilage tissue engineering.

Azmi Baharudin, B. S. Aminuddin, Sharaf Ibrahim, O. C. Samsudin, S. Munirah, Chua Kien Hui, Ruszymah Idrus

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Animal serum is commonly used in chondrocytes culture expansion to promote cell proliferation and shorten the time lag before new tissue reconstruction is possible. However, animal serum is not suitable for regeneration of clinical tissue because it has potential risk of viral and prion related disease transmission particularly mad cow disease and foreign protein contamination that can stimulate immune reaction leading to graft rejection. In this context, human serum as homologous supplement has a greater potential as growth promoting agents for human chondrocytes culture.

Original languageEnglish
Pages (from-to)13-14
Number of pages2
JournalThe Medical journal of Malaysia
Volume59 Suppl B
Publication statusPublished - May 2004

Fingerprint

Articular Cartilage
Tissue Engineering
Chondrocytes
Serum
Bovine Spongiform Encephalopathy
Prion Diseases
Graft Rejection
Regeneration
Cell Proliferation
Growth
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The significance of using pooled human serum in human articular cartilage tissue engineering. / Baharudin, Azmi; Aminuddin, B. S.; Ibrahim, Sharaf; Samsudin, O. C.; Munirah, S.; Kien Hui, Chua; Idrus, Ruszymah.

In: The Medical journal of Malaysia, Vol. 59 Suppl B, 05.2004, p. 13-14.

Research output: Contribution to journalArticle

@article{12903ddd6cd8440ca3b3897821400f36,
title = "The significance of using pooled human serum in human articular cartilage tissue engineering.",
abstract = "Animal serum is commonly used in chondrocytes culture expansion to promote cell proliferation and shorten the time lag before new tissue reconstruction is possible. However, animal serum is not suitable for regeneration of clinical tissue because it has potential risk of viral and prion related disease transmission particularly mad cow disease and foreign protein contamination that can stimulate immune reaction leading to graft rejection. In this context, human serum as homologous supplement has a greater potential as growth promoting agents for human chondrocytes culture.",
author = "Azmi Baharudin and Aminuddin, {B. S.} and Sharaf Ibrahim and Samsudin, {O. C.} and S. Munirah and {Kien Hui}, Chua and Ruszymah Idrus",
year = "2004",
month = "5",
language = "English",
volume = "59 Suppl B",
pages = "13--14",
journal = "Medical Journal of Malaysia",
issn = "0300-5283",
publisher = "Malaysian Medical Association",

}

TY - JOUR

T1 - The significance of using pooled human serum in human articular cartilage tissue engineering.

AU - Baharudin, Azmi

AU - Aminuddin, B. S.

AU - Ibrahim, Sharaf

AU - Samsudin, O. C.

AU - Munirah, S.

AU - Kien Hui, Chua

AU - Idrus, Ruszymah

PY - 2004/5

Y1 - 2004/5

N2 - Animal serum is commonly used in chondrocytes culture expansion to promote cell proliferation and shorten the time lag before new tissue reconstruction is possible. However, animal serum is not suitable for regeneration of clinical tissue because it has potential risk of viral and prion related disease transmission particularly mad cow disease and foreign protein contamination that can stimulate immune reaction leading to graft rejection. In this context, human serum as homologous supplement has a greater potential as growth promoting agents for human chondrocytes culture.

AB - Animal serum is commonly used in chondrocytes culture expansion to promote cell proliferation and shorten the time lag before new tissue reconstruction is possible. However, animal serum is not suitable for regeneration of clinical tissue because it has potential risk of viral and prion related disease transmission particularly mad cow disease and foreign protein contamination that can stimulate immune reaction leading to graft rejection. In this context, human serum as homologous supplement has a greater potential as growth promoting agents for human chondrocytes culture.

UR - http://www.scopus.com/inward/record.url?scp=16544384928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16544384928&partnerID=8YFLogxK

M3 - Article

C2 - 15468795

AN - SCOPUS:16544384928

VL - 59 Suppl B

SP - 13

EP - 14

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

SN - 0300-5283

ER -