The role of endoscopic endonasal approach to pituitary tumours: HUKM experience

Balwant Singh Gendeh, M. Doi, B. M. Selladurai, B. A K Khalid, Jegan Thanabalan, K. Misiran

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Surgery for pituitary tumours at our institution was performed by rhinosurgical route by combined procedure by otolaryngologist and neurosurgeons. A retrospective review of case records of patients who had endonasal endoscopic transphenoidal approach for pituitary tumours from September 1998 to December 2004 was performed. A total of 81 trans-sphenoidal surgeries were performed during this study period. Only 68 case records with adequate information were available for review, 56 patients were included in the study and 12 were excluded. There were 24 males (42%) and 32 females (58%). The ethnic distribution, were 29 Malays, 24 Chinese, 2 Indian and 1 others. The age ranged from 16 years to 76 years, with a mean of 46 years. The majority of our patients presented with visual symptoms (38), headache (28), menstrual cycle disturbance or impotence (14) and acromegalic features (16). Forty patients had macroadenoma (71%) and 16 had microadenomas (29%). Thirty-six patients out of 40 macro-adenomas had suprasellar extensions (90%). Only eleven patients had lumbar drain inserted prior to commencement of the surgery and the majority of these were macroadenomas. The common complications encountered were diabetes insipidus (4), cerebrospinal fluid leak (2), meningitis (3), epistaxis (2), septal perforation (2), intercavernous sinus haemorrhage (3) and anterior pituitary insufficiency (2). Our study reveals that endonasal trans-sphenoidal approach is a safe and effective method of management of pituitary adenomas.

Original languageEnglish
Pages (from-to)343-348
Number of pages6
JournalMedical Journal of Malaysia
Volume61
Issue number3
Publication statusPublished - Aug 2006

Fingerprint

Pituitary Neoplasms
Hypopituitarism
Diabetes Insipidus
Epistaxis
Erectile Dysfunction
Menstrual Cycle
Meningitis
Adenoma
Headache
Hemorrhage

Keywords

  • Complications
  • Endoscopic transphenoidal approach
  • Pituitary tumours
  • Presentation
  • Surgical technique

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gendeh, B. S., Doi, M., Selladurai, B. M., Khalid, B. A. K., Thanabalan, J., & Misiran, K. (2006). The role of endoscopic endonasal approach to pituitary tumours: HUKM experience. Medical Journal of Malaysia, 61(3), 343-348.

The role of endoscopic endonasal approach to pituitary tumours : HUKM experience. / Gendeh, Balwant Singh; Doi, M.; Selladurai, B. M.; Khalid, B. A K; Thanabalan, Jegan; Misiran, K.

In: Medical Journal of Malaysia, Vol. 61, No. 3, 08.2006, p. 343-348.

Research output: Contribution to journalArticle

Gendeh, BS, Doi, M, Selladurai, BM, Khalid, BAK, Thanabalan, J & Misiran, K 2006, 'The role of endoscopic endonasal approach to pituitary tumours: HUKM experience', Medical Journal of Malaysia, vol. 61, no. 3, pp. 343-348.
Gendeh, Balwant Singh ; Doi, M. ; Selladurai, B. M. ; Khalid, B. A K ; Thanabalan, Jegan ; Misiran, K. / The role of endoscopic endonasal approach to pituitary tumours : HUKM experience. In: Medical Journal of Malaysia. 2006 ; Vol. 61, No. 3. pp. 343-348.
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