The risk factors of gastrointestinal bleeding in acute ischaemic stroke

Bin Basri Hamidon, Raymond Azman Ali

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Gastrointestinal (GI) bleeding is one of the most serious complications after an acute ischaemic stroke and may affect stroke outcome. We identified predictors and the eventual outcome of gastrointestinal bleeding during the in-patient period following the commencement of aspirin. This was a study of patients with acute ischaemic stroke admitted to Universiti Kebangsaan Malaysia Hospital from June 2000 to January 2001. A single observer, using pre-defined diagnostic criteria recorded information on demography, risk factors and GI bleeding that occurred during the inpatient period. One hundred and fifteen patients with acute ischaemic stroke were enrolled in the study. Gastrointestinal bleeding was observed in 6 (5.2%) patients. Using univariate analysis, the independent predictors of gastrointestinal bleeding were age (OR 1.25; 95% CI 1.07 to 1.50), and middle cerebral artery (MCA) territory infarcts (OR 9.47; 95% CI 1.62 to 55.5). Using multivariate analysis, the presence of gastrointestinal bleeding increased mortality (OR 24.97; 95% CI 1.97 to 316.91). Older age, and large MCA infarct predict the development gastrointestinal bleeding. Stroke mortality was independently predicted by gastrointestinal bleeding. Prophylactic treatment in elderly patients with large cerebral infarcts may be an area for further investigation.

Original languageEnglish
Pages (from-to)288-291
Number of pages4
JournalMedical Journal of Malaysia
Volume61
Issue number3
Publication statusPublished - Aug 2006

Fingerprint

Stroke
Hemorrhage
Middle Cerebral Artery
Mortality
Malaysia
Aspirin
Inpatients
Multivariate Analysis
Demography

Keywords

  • Gastrointestinal bleeding
  • Ischaemic stroke
  • Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The risk factors of gastrointestinal bleeding in acute ischaemic stroke. / Hamidon, Bin Basri; Ali, Raymond Azman.

In: Medical Journal of Malaysia, Vol. 61, No. 3, 08.2006, p. 288-291.

Research output: Contribution to journalArticle

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