Abstract
Purpose: The purpose of this study was to investigate the association between long-term intranasal steroid use and intraocular pressure (IOP) elevation. Patients and Methods: In total, 100 eyes from 50 patients on long-term intranasal steroids (>2 y) for allergic rhinitis and 90 eyes from 45 controls were included in this study. Patients on other forms of steroids and risk factors for glaucoma were excluded. IOP was measured and nonmydriatic stereoscopic optic disc photos were taken for each eye. The vertical cup-to-disc ratio and the status of the optic disc were evaluated. Results: The mean IOP for intranasal steroids group was significantly higher (15.24±2.31 mm Hg) compared to the control group (13.91±1.86 mm Hg; P=0.000). However, there were no significant differences in the vertical cup-to-disc ratio and the status of glaucomatous optic disc changes between the groups. Conclusions: Prolonged use of intranasal steroids cause statistical significant increase in IOP in patients with allergic rhinitis although no significant glaucomatous disc changes were seen. We suggest patients on long-term use of intranasal steroid have a yearly eye examination to be monitored for IOP elevation and those with additional risk factors for glaucoma is closely monitored for glaucoma.
| Original language | English |
|---|---|
| Pages (from-to) | 321-324 |
| Number of pages | 4 |
| Journal | Journal of Glaucoma |
| Volume | 28 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2019 |
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Keywords
- glaucoma
- intranasal corticosteroid
- intraocular pressure
ASJC Scopus subject areas
- Ophthalmology
Cite this
The Relationship between Long-term Use of Intranasal Corticosteroid and Intraocular Pressure. / Mohd Zain, Ayesha; Md Noh, Umi Kalthum; Hussein, Salina; Che Hamzah, Jemaima; Mohd Khialdin, Safinaz; Md. Din, Norshamsiah.
In: Journal of Glaucoma, Vol. 28, No. 4, 01.04.2019, p. 321-324.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The Relationship between Long-term Use of Intranasal Corticosteroid and Intraocular Pressure
AU - Mohd Zain, Ayesha
AU - Md Noh, Umi Kalthum
AU - Hussein, Salina
AU - Che Hamzah, Jemaima
AU - Mohd Khialdin, Safinaz
AU - Md. Din, Norshamsiah
PY - 2019/4/1
Y1 - 2019/4/1
N2 - Purpose: The purpose of this study was to investigate the association between long-term intranasal steroid use and intraocular pressure (IOP) elevation. Patients and Methods: In total, 100 eyes from 50 patients on long-term intranasal steroids (>2 y) for allergic rhinitis and 90 eyes from 45 controls were included in this study. Patients on other forms of steroids and risk factors for glaucoma were excluded. IOP was measured and nonmydriatic stereoscopic optic disc photos were taken for each eye. The vertical cup-to-disc ratio and the status of the optic disc were evaluated. Results: The mean IOP for intranasal steroids group was significantly higher (15.24±2.31 mm Hg) compared to the control group (13.91±1.86 mm Hg; P=0.000). However, there were no significant differences in the vertical cup-to-disc ratio and the status of glaucomatous optic disc changes between the groups. Conclusions: Prolonged use of intranasal steroids cause statistical significant increase in IOP in patients with allergic rhinitis although no significant glaucomatous disc changes were seen. We suggest patients on long-term use of intranasal steroid have a yearly eye examination to be monitored for IOP elevation and those with additional risk factors for glaucoma is closely monitored for glaucoma.
AB - Purpose: The purpose of this study was to investigate the association between long-term intranasal steroid use and intraocular pressure (IOP) elevation. Patients and Methods: In total, 100 eyes from 50 patients on long-term intranasal steroids (>2 y) for allergic rhinitis and 90 eyes from 45 controls were included in this study. Patients on other forms of steroids and risk factors for glaucoma were excluded. IOP was measured and nonmydriatic stereoscopic optic disc photos were taken for each eye. The vertical cup-to-disc ratio and the status of the optic disc were evaluated. Results: The mean IOP for intranasal steroids group was significantly higher (15.24±2.31 mm Hg) compared to the control group (13.91±1.86 mm Hg; P=0.000). However, there were no significant differences in the vertical cup-to-disc ratio and the status of glaucomatous optic disc changes between the groups. Conclusions: Prolonged use of intranasal steroids cause statistical significant increase in IOP in patients with allergic rhinitis although no significant glaucomatous disc changes were seen. We suggest patients on long-term use of intranasal steroid have a yearly eye examination to be monitored for IOP elevation and those with additional risk factors for glaucoma is closely monitored for glaucoma.
KW - glaucoma
KW - intranasal corticosteroid
KW - intraocular pressure
UR - http://www.scopus.com/inward/record.url?scp=85064239120&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064239120&partnerID=8YFLogxK
U2 - 10.1097/IJG.0000000000001164
DO - 10.1097/IJG.0000000000001164
M3 - Article
VL - 28
SP - 321
EP - 324
JO - Journal of Glaucoma
JF - Journal of Glaucoma
SN - 1057-0829
IS - 4
ER -