The predictors of early infection after an acute ischaemic stroke

Bin Basri Hamidon, Raymond Azman Ali, Norlinah Mohamed Ibrahim, S. B. Jefferelli

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47 Citations (Scopus)

Abstract

Background and purpose: Infection is a frequent complication after an acute stroke and may affect stroke outcome. We identified predictors of early infection, type of infection, their relation to initial disability, and the eventual outcome during the inpatient period. Methods: This was a study of patients with acute ischaemic stroke admitted to Universiti Kebangsaan Malaysia Hospital from June 2000 to January 2001. A single observer, using pre-defined diagnostic criteria recorded information on demography, the type, time of onset, and frequency of infections that occurred during the inpatient period. Results: One hundred and sixty three patients with acute ischaemic stroke were enrolled in the study. Early infection was observed in 26 (16%) patients. The infections observed were pneumonia (12.3%), and urinary tract infection (3.7%). Using multivariate analysis, the independent predictors of early infection were Barthel index (BI) less than 5 (OR 4.23; 95%CI 1.70 to 5.11), middle cerebral artery (MCA) territory infarcts (OR 4.91; 95%CI 1.57 to 8.82), and a Glasgow coma score (GCS) less than 9 (OR 5.12; 95%CI 2.98 to 15.52). The presence of early infection increased mortality (OR 14.83; 95%CI 4.31 to 51.07). Conclusions: Severe disability, large MCA infarct and poor GCS independently predict the development of early infection.

Original languageEnglish
Pages (from-to)344-346
Number of pages3
JournalSingapore Medical Journal
Volume44
Issue number7
Publication statusPublished - 1 Jul 2003

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Stroke
Infection
Middle Cerebral Artery
Coma
Inpatients
Malaysia
Urinary Tract Infections
Pneumonia
Multivariate Analysis
Demography
Mortality

Keywords

  • Early infection
  • Ischaemic stroke
  • Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

The predictors of early infection after an acute ischaemic stroke. / Hamidon, Bin Basri; Ali, Raymond Azman; Mohamed Ibrahim, Norlinah; Jefferelli, S. B.

In: Singapore Medical Journal, Vol. 44, No. 7, 01.07.2003, p. 344-346.

Research output: Contribution to journalArticle

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