The potential of dendrimer in delivery of therapeutics for dentistry

Ranjeet A. Bapat, Suyog Dharmadhikari, Tanay V. Chaubal, Mohd Cairul Iqbal Mohd Amin, Prachi Bapat, Bapi Gorain, Hira Choudhury, Christopher Vincent, Prashant Kesharwani

Research output: Contribution to journalArticle

Abstract

Dendrimers are hyperbranched nanoparticle structures along with its surface modifications can to be used in dental biomaterials for biomimetic remineralisation of enamel and dentin. The review highlights the therapeutic applications of dendrimers in the field of dentistry. It addresses the possible mechanisms of enhancement of mechanical properties of adhesives and resins structure. Dendrimers due to its unique construction of possessing inner hydrophobic and outer hydrophilic structure can act as drug carrier for delivery of antimicrobial drugs for treatment of periodontal diseases and at peripheral dental implant areas. Dendrimers due to its hyperbranched structures can provides a unique drug delivery vehicle for delivery of a drug at specific site for sustained release for therapeutic effects. Thus, dendrimers can be one of the most important constituents which can be incorporated in dental biomaterials for better outcomes in dentistry.

Original languageEnglish
Article numbere02544
JournalHeliyon
Volume5
Issue number10
DOIs
Publication statusPublished - Oct 2019

Fingerprint

Dendrimers
Dentistry
Biocompatible Materials
Tooth
Pharmaceutical Preparations
Therapeutics
Biomimetics
Drug Carriers
Dental Implants
Periodontal Diseases
Therapeutic Uses
Dentin
Dental Enamel
Adhesives
Nanoparticles

Keywords

  • Adhesives
  • Antimicrobial
  • Biomimetic
  • Dendrimers
  • Dental plaque
  • Dentistry
  • Materials science
  • Periodontal

ASJC Scopus subject areas

  • General

Cite this

Bapat, R. A., Dharmadhikari, S., Chaubal, T. V., Amin, M. C. I. M., Bapat, P., Gorain, B., ... Kesharwani, P. (2019). The potential of dendrimer in delivery of therapeutics for dentistry. Heliyon, 5(10), [e02544]. https://doi.org/10.1016/j.heliyon.2019.e02544

The potential of dendrimer in delivery of therapeutics for dentistry. / Bapat, Ranjeet A.; Dharmadhikari, Suyog; Chaubal, Tanay V.; Amin, Mohd Cairul Iqbal Mohd; Bapat, Prachi; Gorain, Bapi; Choudhury, Hira; Vincent, Christopher; Kesharwani, Prashant.

In: Heliyon, Vol. 5, No. 10, e02544, 10.2019.

Research output: Contribution to journalArticle

Bapat, RA, Dharmadhikari, S, Chaubal, TV, Amin, MCIM, Bapat, P, Gorain, B, Choudhury, H, Vincent, C & Kesharwani, P 2019, 'The potential of dendrimer in delivery of therapeutics for dentistry', Heliyon, vol. 5, no. 10, e02544. https://doi.org/10.1016/j.heliyon.2019.e02544
Bapat RA, Dharmadhikari S, Chaubal TV, Amin MCIM, Bapat P, Gorain B et al. The potential of dendrimer in delivery of therapeutics for dentistry. Heliyon. 2019 Oct;5(10). e02544. https://doi.org/10.1016/j.heliyon.2019.e02544
Bapat, Ranjeet A. ; Dharmadhikari, Suyog ; Chaubal, Tanay V. ; Amin, Mohd Cairul Iqbal Mohd ; Bapat, Prachi ; Gorain, Bapi ; Choudhury, Hira ; Vincent, Christopher ; Kesharwani, Prashant. / The potential of dendrimer in delivery of therapeutics for dentistry. In: Heliyon. 2019 ; Vol. 5, No. 10.
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