The poisoned patient

Choo Hock Tan, Ahmad Khaldun Ismail

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Acute exposure to toxic or poisonous substances can be intentional or accidental. The onset of the toxic effect depends on the degree of absorption of the toxicant. The management of acute exposure to toxicants is generally supportive. Knowledge of the pharmacokinetics and pharmacodynamics of the offending agent is important. The use of pharmacological agents in treating poisoning is to manipulate the pharmacokinetic or pharmacodynamic profiles of the toxicant. These pharmacological agents will minimize the absorption and/or enhance the elimination of the toxicant from the body. Specific antidotes are used to alter the effects of certain known toxicants through neutralization and pharmacological antagonism. Having the ability to identify the effect of specific classes of substances on the body (toxidromes) will facilitate the selection of an appropriate management strategy to optimize the outcome.

Original languageEnglish
Title of host publicationPharmacological Basis of Acute Care
PublisherSpringer International Publishing
Pages219-225
Number of pages7
ISBN (Print)9783319103860, 9783319103853
DOIs
Publication statusPublished - 1 Jan 2015
Externally publishedYes

Fingerprint

Poisons
Pharmacology
Pharmacokinetics
Antidotes
Poisoning

Keywords

  • Antagonism
  • Antidote
  • Medical toxicology
  • Neutralization
  • Poison
  • Rebound phenomenon
  • Toxicant
  • Toxin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tan, C. H., & Ismail, A. K. (2015). The poisoned patient. In Pharmacological Basis of Acute Care (pp. 219-225). Springer International Publishing. https://doi.org/10.1007/978-3-319-10386-0_27

The poisoned patient. / Tan, Choo Hock; Ismail, Ahmad Khaldun.

Pharmacological Basis of Acute Care. Springer International Publishing, 2015. p. 219-225.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tan, CH & Ismail, AK 2015, The poisoned patient. in Pharmacological Basis of Acute Care. Springer International Publishing, pp. 219-225. https://doi.org/10.1007/978-3-319-10386-0_27
Tan CH, Ismail AK. The poisoned patient. In Pharmacological Basis of Acute Care. Springer International Publishing. 2015. p. 219-225 https://doi.org/10.1007/978-3-319-10386-0_27
Tan, Choo Hock ; Ismail, Ahmad Khaldun. / The poisoned patient. Pharmacological Basis of Acute Care. Springer International Publishing, 2015. pp. 219-225
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