The hyperactivity of efferent auditory system in patients with schizophrenia

A transient evoked otoacoustic emissions study

Noor Alaudin Abdul Wahab, Suzaily Wahab, Abdul Hamid Abdul Rahman, Dinsuhaimi Sidek, Mohd Normani Zakaria

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory pathway on cochlear outer hair cells among schizophrenia patients are limited. The present, case-control, study examined the contralateral suppression of transient evoked otoacoustic emissions (TEOAEs) in patients with schizophrenia. Methods Participants were twenty-three healthy controls and sixteen schizophrenia patients with normal hearing, middle ear and cochlear outer hair cells function. Absolute non-linear and linear TEOAEs were measured in both ears by delivering clicks stimuli at 80 dB SPL and 60 dB SPL respectively. Subsequently, contralateral suppression was determined by subtracting the absolute TEOAEs response obtained at 60 dBpe SPL during the absence and presence of contralateral white noise delivered at 65 dB HL. No attention tasks were conducted during measurements. Results We found no significant difference in absolute TEOAEs responses at 80 dB SPL, in either diagnosis or ear groups (p>0.05). However, the overall contralateral suppression was significantly larger in schizophrenia patients (p

Original languageEnglish
Pages (from-to)82-88
Number of pages7
JournalPsychiatry Investigation
Volume13
Issue number1
DOIs
Publication statusPublished - 1 Jan 2016

Fingerprint

Schizophrenia
Outer Auditory Hair Cells
Ear
Afferent Pathways
Auditory Pathways
Efferent Pathways
Middle Ear
Hearing
Case-Control Studies

Keywords

  • Efferent pathways
  • Hair cells
  • Otoacoustic emissions
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

The hyperactivity of efferent auditory system in patients with schizophrenia : A transient evoked otoacoustic emissions study. / Abdul Wahab, Noor Alaudin; Wahab, Suzaily; Abdul Rahman, Abdul Hamid; Sidek, Dinsuhaimi; Zakaria, Mohd Normani.

In: Psychiatry Investigation, Vol. 13, No. 1, 01.01.2016, p. 82-88.

Research output: Contribution to journalArticle

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