The genus Polygonum (Polygonaceae): An ethnopharmacological and phytochemical perspectives - Review

Ganapathi Narasimhulu, Kesireddy Kathyvevelu Reddy, Jamaludin Mohamed

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The genus Polygonum (Polygonaceae), comprising about 300 species, is distributed worldwide, mostly in north temperate climates, is interesting from both biological and phytochemical perspectives. In this review, a contemporary summary of biological and pharmacological investigate on Polygonum species will be presented and critically evaluated. Significant findings in the treatment various diseases such as snake-bites, inflammatory, anticancer, antibacterial, antivirus, antiseptic, antifungal, diabetic, hypertension, hyperlipemia, jaundice, hemorrhage, cough, fever, ulcers, skin affections, anemia, diarrhea and various urologic disorders, have been presented in ethnobotanical reports and recent studies were performed on ethanol extracts for certain Polygonum species. Polygonum, the most important constituent isolated is known to possess anticancer activity. Very few additional data are available on the biological activities and cytotoxicity of pure compounds from Polygonum. Twenty-nine distinguished species of Polygonum have been reported in scientific literature as ethnobotanically used or phytochemically investigated. However, information about a chemical outline is available only for few species. The following review gives a critical assessment of the literature to date and aims to show that the pharmaceutical potential of this genus has been underestimated and deserves closer attention.

Original languageEnglish
Pages (from-to)21-45
Number of pages25
JournalInternational Journal of Pharmacy and Pharmaceutical Sciences
Volume6
Issue number2
Publication statusPublished - 2014

Fingerprint

Polygonaceae
Polygonum
Phytochemicals
Skin Ulcer
Literature
Snake Bites
Local Anti-Infective Agents
Jaundice
Hyperlipidemias
Climate
Cough
Anemia
Diarrhea
Fever
Ethanol
Pharmacology
Hemorrhage
Hypertension

Keywords

  • Pharmacology
  • Phytochemistry
  • Polygonum
  • Traditional medicine

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

Cite this

The genus Polygonum (Polygonaceae) : An ethnopharmacological and phytochemical perspectives - Review. / Narasimhulu, Ganapathi; Reddy, Kesireddy Kathyvevelu; Mohamed, Jamaludin.

In: International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 6, No. 2, 2014, p. 21-45.

Research output: Contribution to journalArticle

Narasimhulu, Ganapathi ; Reddy, Kesireddy Kathyvevelu ; Mohamed, Jamaludin. / The genus Polygonum (Polygonaceae) : An ethnopharmacological and phytochemical perspectives - Review. In: International Journal of Pharmacy and Pharmaceutical Sciences. 2014 ; Vol. 6, No. 2. pp. 21-45.
@article{bc70dbbb90f04503832ef61fc73cdbb1,
title = "The genus Polygonum (Polygonaceae): An ethnopharmacological and phytochemical perspectives - Review",
abstract = "The genus Polygonum (Polygonaceae), comprising about 300 species, is distributed worldwide, mostly in north temperate climates, is interesting from both biological and phytochemical perspectives. In this review, a contemporary summary of biological and pharmacological investigate on Polygonum species will be presented and critically evaluated. Significant findings in the treatment various diseases such as snake-bites, inflammatory, anticancer, antibacterial, antivirus, antiseptic, antifungal, diabetic, hypertension, hyperlipemia, jaundice, hemorrhage, cough, fever, ulcers, skin affections, anemia, diarrhea and various urologic disorders, have been presented in ethnobotanical reports and recent studies were performed on ethanol extracts for certain Polygonum species. Polygonum, the most important constituent isolated is known to possess anticancer activity. Very few additional data are available on the biological activities and cytotoxicity of pure compounds from Polygonum. Twenty-nine distinguished species of Polygonum have been reported in scientific literature as ethnobotanically used or phytochemically investigated. However, information about a chemical outline is available only for few species. The following review gives a critical assessment of the literature to date and aims to show that the pharmaceutical potential of this genus has been underestimated and deserves closer attention.",
keywords = "Pharmacology, Phytochemistry, Polygonum, Traditional medicine",
author = "Ganapathi Narasimhulu and Reddy, {Kesireddy Kathyvevelu} and Jamaludin Mohamed",
year = "2014",
language = "English",
volume = "6",
pages = "21--45",
journal = "International Journal of Pharmacy and Pharmaceutical Sciences",
issn = "0975-1491",
publisher = "IJPPS",
number = "2",

}

TY - JOUR

T1 - The genus Polygonum (Polygonaceae)

T2 - An ethnopharmacological and phytochemical perspectives - Review

AU - Narasimhulu, Ganapathi

AU - Reddy, Kesireddy Kathyvevelu

AU - Mohamed, Jamaludin

PY - 2014

Y1 - 2014

N2 - The genus Polygonum (Polygonaceae), comprising about 300 species, is distributed worldwide, mostly in north temperate climates, is interesting from both biological and phytochemical perspectives. In this review, a contemporary summary of biological and pharmacological investigate on Polygonum species will be presented and critically evaluated. Significant findings in the treatment various diseases such as snake-bites, inflammatory, anticancer, antibacterial, antivirus, antiseptic, antifungal, diabetic, hypertension, hyperlipemia, jaundice, hemorrhage, cough, fever, ulcers, skin affections, anemia, diarrhea and various urologic disorders, have been presented in ethnobotanical reports and recent studies were performed on ethanol extracts for certain Polygonum species. Polygonum, the most important constituent isolated is known to possess anticancer activity. Very few additional data are available on the biological activities and cytotoxicity of pure compounds from Polygonum. Twenty-nine distinguished species of Polygonum have been reported in scientific literature as ethnobotanically used or phytochemically investigated. However, information about a chemical outline is available only for few species. The following review gives a critical assessment of the literature to date and aims to show that the pharmaceutical potential of this genus has been underestimated and deserves closer attention.

AB - The genus Polygonum (Polygonaceae), comprising about 300 species, is distributed worldwide, mostly in north temperate climates, is interesting from both biological and phytochemical perspectives. In this review, a contemporary summary of biological and pharmacological investigate on Polygonum species will be presented and critically evaluated. Significant findings in the treatment various diseases such as snake-bites, inflammatory, anticancer, antibacterial, antivirus, antiseptic, antifungal, diabetic, hypertension, hyperlipemia, jaundice, hemorrhage, cough, fever, ulcers, skin affections, anemia, diarrhea and various urologic disorders, have been presented in ethnobotanical reports and recent studies were performed on ethanol extracts for certain Polygonum species. Polygonum, the most important constituent isolated is known to possess anticancer activity. Very few additional data are available on the biological activities and cytotoxicity of pure compounds from Polygonum. Twenty-nine distinguished species of Polygonum have been reported in scientific literature as ethnobotanically used or phytochemically investigated. However, information about a chemical outline is available only for few species. The following review gives a critical assessment of the literature to date and aims to show that the pharmaceutical potential of this genus has been underestimated and deserves closer attention.

KW - Pharmacology

KW - Phytochemistry

KW - Polygonum

KW - Traditional medicine

UR - http://www.scopus.com/inward/record.url?scp=84897142165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897142165&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84897142165

VL - 6

SP - 21

EP - 45

JO - International Journal of Pharmacy and Pharmaceutical Sciences

JF - International Journal of Pharmacy and Pharmaceutical Sciences

SN - 0975-1491

IS - 2

ER -