The effects of aging on the brain activation pattern during a speech perception task

an fMRI study

Hanani Abdul Manan, Elizabeth A. Franz, Ahmad Nazlim Yusoff, Siti Zamratol Mai Sarah Mukari

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In the present study, brain activation associated with speech perception processing was examined across four groups of adult participants with age ranges between 20 and 65 years, using functional MRI (fMRI). Cognitive performance demonstrates that performance accuracy declines with age. fMRI results reveal that all four groups of participants activated the same brain areas. The same brain activation pattern was found in all activated areas (except for the right superior temporal gyrus and right middle temporal gyrus); brain activity was increased from group 1 (20–29 years) to group 2 (30–39 years). However, it decreased in group 3 (40–49 years) with further decreases in group 4 participants (50–65 years). Result also reveals that three brain areas (superior temporal gyrus, Heschl’s gyrus and cerebellum) showed changes in brain laterality in the older participants, akin to a shift from left-lateralized to right-lateralized activity. The onset of this change was different across brain areas. Based on these findings we suggest that, whereas all four groups of participants used the same areas in processing, the engagement and recruitment of those areas differ with age as the brain grows older. Findings are discussed in the context of corroborating evidence of neural changes with age.

Original languageEnglish
Pages (from-to)27-36
Number of pages10
JournalAging clinical and experimental research
Volume27
Issue number1
DOIs
Publication statusPublished - 1 Feb 2015

Fingerprint

Speech Perception
Magnetic Resonance Imaging
Brain
Temporal Lobe
Auditory Cortex
Cerebellum

Keywords

  • Brain laterality
  • fMRI
  • Neural deterioration
  • Speech perception processing

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

The effects of aging on the brain activation pattern during a speech perception task : an fMRI study. / Manan, Hanani Abdul; Franz, Elizabeth A.; Yusoff, Ahmad Nazlim; Mukari, Siti Zamratol Mai Sarah.

In: Aging clinical and experimental research, Vol. 27, No. 1, 01.02.2015, p. 27-36.

Research output: Contribution to journalArticle

Manan, Hanani Abdul ; Franz, Elizabeth A. ; Yusoff, Ahmad Nazlim ; Mukari, Siti Zamratol Mai Sarah. / The effects of aging on the brain activation pattern during a speech perception task : an fMRI study. In: Aging clinical and experimental research. 2015 ; Vol. 27, No. 1. pp. 27-36.
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