The effect of low electromagnetic field in the cerebellar layers of mice

Yanti Rosli, P. J. Teoh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The study on the effects of low electromagnetic fields (EMF) towards human health has been ongoing for over three decades but it is inconclusive still as to whether or not EMF is harmful to human health. This study was undertaken to look at the effects of EMF exposure on the morphology of the cerebellum of adult mice and offspring of pregnant mice which were exposed to EMF during their gestational period. The intensity of EMF used in this study was 1.2 mT and 0 mT for treatment group and control group, respectively. The adult mice were exposed to EMF 5 days consecutively, each exposure session lasting for 6 h. The prenatal exposure was done on gestation day 3, 6, 9, 12 and 15. Then, the thickness of Granular Layer (GL) and Molecular Layer (ML) were measured using an image analyzer. Statistical analysis showed that there was a significant decrease in the number of Purkinje Cells (PCS), a decrease in the thickness of both the GL and ML in the 1.2 mT adult treatment group (p<0.001). In the offspring exposed prenatally, the number of PCS were also significantly decreased (p<0.001), but significant thickening of the GL (p<0.05) was observed in the 1.2 mT treatment group. The results obtained in this study, suggest that the exposure to EMF can cause changes to the morphology of cerebellum of adult mice and also affects the development of mice cerebellum.

Original languageEnglish
Pages (from-to)601-606
Number of pages6
JournalJournal of Biological Sciences
Volume9
Issue number6
DOIs
Publication statusPublished - 2009

Fingerprint

Electromagnetic Fields
Cerebellum
Purkinje Cells
Health
Pregnancy
Control Groups

Keywords

  • Cerebellum
  • Electromagnetic field
  • EMF
  • Purkinjie cells

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Medicine

Cite this

The effect of low electromagnetic field in the cerebellar layers of mice. / Rosli, Yanti; Teoh, P. J.

In: Journal of Biological Sciences, Vol. 9, No. 6, 2009, p. 601-606.

Research output: Contribution to journalArticle

@article{47a85b7328194aeca71632709adefc52,
title = "The effect of low electromagnetic field in the cerebellar layers of mice",
abstract = "The study on the effects of low electromagnetic fields (EMF) towards human health has been ongoing for over three decades but it is inconclusive still as to whether or not EMF is harmful to human health. This study was undertaken to look at the effects of EMF exposure on the morphology of the cerebellum of adult mice and offspring of pregnant mice which were exposed to EMF during their gestational period. The intensity of EMF used in this study was 1.2 mT and 0 mT for treatment group and control group, respectively. The adult mice were exposed to EMF 5 days consecutively, each exposure session lasting for 6 h. The prenatal exposure was done on gestation day 3, 6, 9, 12 and 15. Then, the thickness of Granular Layer (GL) and Molecular Layer (ML) were measured using an image analyzer. Statistical analysis showed that there was a significant decrease in the number of Purkinje Cells (PCS), a decrease in the thickness of both the GL and ML in the 1.2 mT adult treatment group (p<0.001). In the offspring exposed prenatally, the number of PCS were also significantly decreased (p<0.001), but significant thickening of the GL (p<0.05) was observed in the 1.2 mT treatment group. The results obtained in this study, suggest that the exposure to EMF can cause changes to the morphology of cerebellum of adult mice and also affects the development of mice cerebellum.",
keywords = "Cerebellum, Electromagnetic field, EMF, Purkinjie cells",
author = "Yanti Rosli and Teoh, {P. J.}",
year = "2009",
doi = "10.3923/jbs.2009.601.606",
language = "English",
volume = "9",
pages = "601--606",
journal = "Journal of Biological Sciences",
issn = "1727-3048",
publisher = "Asian Network for Scientific Information",
number = "6",

}

TY - JOUR

T1 - The effect of low electromagnetic field in the cerebellar layers of mice

AU - Rosli, Yanti

AU - Teoh, P. J.

PY - 2009

Y1 - 2009

N2 - The study on the effects of low electromagnetic fields (EMF) towards human health has been ongoing for over three decades but it is inconclusive still as to whether or not EMF is harmful to human health. This study was undertaken to look at the effects of EMF exposure on the morphology of the cerebellum of adult mice and offspring of pregnant mice which were exposed to EMF during their gestational period. The intensity of EMF used in this study was 1.2 mT and 0 mT for treatment group and control group, respectively. The adult mice were exposed to EMF 5 days consecutively, each exposure session lasting for 6 h. The prenatal exposure was done on gestation day 3, 6, 9, 12 and 15. Then, the thickness of Granular Layer (GL) and Molecular Layer (ML) were measured using an image analyzer. Statistical analysis showed that there was a significant decrease in the number of Purkinje Cells (PCS), a decrease in the thickness of both the GL and ML in the 1.2 mT adult treatment group (p<0.001). In the offspring exposed prenatally, the number of PCS were also significantly decreased (p<0.001), but significant thickening of the GL (p<0.05) was observed in the 1.2 mT treatment group. The results obtained in this study, suggest that the exposure to EMF can cause changes to the morphology of cerebellum of adult mice and also affects the development of mice cerebellum.

AB - The study on the effects of low electromagnetic fields (EMF) towards human health has been ongoing for over three decades but it is inconclusive still as to whether or not EMF is harmful to human health. This study was undertaken to look at the effects of EMF exposure on the morphology of the cerebellum of adult mice and offspring of pregnant mice which were exposed to EMF during their gestational period. The intensity of EMF used in this study was 1.2 mT and 0 mT for treatment group and control group, respectively. The adult mice were exposed to EMF 5 days consecutively, each exposure session lasting for 6 h. The prenatal exposure was done on gestation day 3, 6, 9, 12 and 15. Then, the thickness of Granular Layer (GL) and Molecular Layer (ML) were measured using an image analyzer. Statistical analysis showed that there was a significant decrease in the number of Purkinje Cells (PCS), a decrease in the thickness of both the GL and ML in the 1.2 mT adult treatment group (p<0.001). In the offspring exposed prenatally, the number of PCS were also significantly decreased (p<0.001), but significant thickening of the GL (p<0.05) was observed in the 1.2 mT treatment group. The results obtained in this study, suggest that the exposure to EMF can cause changes to the morphology of cerebellum of adult mice and also affects the development of mice cerebellum.

KW - Cerebellum

KW - Electromagnetic field

KW - EMF

KW - Purkinjie cells

UR - http://www.scopus.com/inward/record.url?scp=67650649500&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67650649500&partnerID=8YFLogxK

U2 - 10.3923/jbs.2009.601.606

DO - 10.3923/jbs.2009.601.606

M3 - Article

AN - SCOPUS:67650649500

VL - 9

SP - 601

EP - 606

JO - Journal of Biological Sciences

JF - Journal of Biological Sciences

SN - 1727-3048

IS - 6

ER -