The effect of CO2 laser treatment on skin tissue

Sana Mohammed Anayb Baleg, Noriah Bidin, Lau Pik Suan, Muhammad Fakarruddin Sidi Ahmad, Ganesan Krishnan, Abd Rahman Johari, Asmah Hamid

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background/Objective: The aim of this study was to evaluate the effects of multiple pulses on the depth of injury caused by CO2 laser in an in vivo rat model. Methods: A 10 600-nm CO2 laser was applied to rat skin, with one side of the rat dorsal skin being exposed, leaving the other side as a control. Results: All of the various laser pulses tested led to gradual loss of epidermal thickness as well as a dramatic increase in thermal damage depth. Collagen coagulation was most effective with ten pulses of CO2 laser, while the strength of irradiated skin tissue increased as the influence of the laser increased. Conclusion: Fundamental laser-skin interaction effects were studied using a CO2 laser. The photodamaged areas obtained from laser interaction were recorded via couple charge device video camera and analyzed via ImageJ software. Photodamage induced by CO2 laser is due to photothermal effects, which involve burning and vaporizing mechanisms to ablate the epidermis layer. The burning area literally expands and penetrates deep into the dermis layer, subsequently causing collagen coagulation. This fundamental study shows in detail the effect of CO2 laser interaction with skin. The CO2 attributed severe burning, producing deep coagulation, and induced strength to treated skin.

Original languageEnglish
Pages (from-to)246-253
Number of pages8
JournalJournal of Cosmetic Dermatology
Volume14
Issue number3
DOIs
Publication statusPublished - 1 Sep 2015

Fingerprint

Gas Lasers
Skin
Lasers
Collagen
Dermis
Epidermis
Software
Hot Temperature
Equipment and Supplies
Wounds and Injuries

Keywords

  • CO<inf>2</inf> laser
  • Photodamage
  • Skin tissue
  • Thermal depth

ASJC Scopus subject areas

  • Dermatology

Cite this

Baleg, S. M. A., Bidin, N., Suan, L. P., Ahmad, M. F. S., Krishnan, G., Johari, A. R., & Hamid, A. (2015). The effect of CO2 laser treatment on skin tissue. Journal of Cosmetic Dermatology, 14(3), 246-253. https://doi.org/10.1111/jocd.12142

The effect of CO2 laser treatment on skin tissue. / Baleg, Sana Mohammed Anayb; Bidin, Noriah; Suan, Lau Pik; Ahmad, Muhammad Fakarruddin Sidi; Krishnan, Ganesan; Johari, Abd Rahman; Hamid, Asmah.

In: Journal of Cosmetic Dermatology, Vol. 14, No. 3, 01.09.2015, p. 246-253.

Research output: Contribution to journalArticle

Baleg, SMA, Bidin, N, Suan, LP, Ahmad, MFS, Krishnan, G, Johari, AR & Hamid, A 2015, 'The effect of CO2 laser treatment on skin tissue', Journal of Cosmetic Dermatology, vol. 14, no. 3, pp. 246-253. https://doi.org/10.1111/jocd.12142
Baleg SMA, Bidin N, Suan LP, Ahmad MFS, Krishnan G, Johari AR et al. The effect of CO2 laser treatment on skin tissue. Journal of Cosmetic Dermatology. 2015 Sep 1;14(3):246-253. https://doi.org/10.1111/jocd.12142
Baleg, Sana Mohammed Anayb ; Bidin, Noriah ; Suan, Lau Pik ; Ahmad, Muhammad Fakarruddin Sidi ; Krishnan, Ganesan ; Johari, Abd Rahman ; Hamid, Asmah. / The effect of CO2 laser treatment on skin tissue. In: Journal of Cosmetic Dermatology. 2015 ; Vol. 14, No. 3. pp. 246-253.
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