Testosterone is associated with age-related changes in bone health status, muscle strength and body composition in men

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objective: Variations in testosterone levels are associated with several outcomes of aging. The present study aimed to examine the relationship between age-related decline of testosterone levels and changes in bone health status, handgrip strength, body fat percentage and fat-free mass. Materials and methods: A total of 335 Malaysian Chinese and Malay men aged 40 years and above were recruited for this study. Their body compositions, calcaneal speed of sound and handgrip strength were measured and their blood was collected. Linear regression analysis was done to examine the relationship among age, testosterone levels and outcomes of aging. Results: The results indicated significant changes in all testosterone measurements, sex hormone binding globulin level, calcaneal speed of sound, handgrip strength, body fat percentage and fat-free mass with age (p < 0.05). Age-dependent decline in bioavailable and free testosterone levels were significantly associated with reduction in calcaneal speed of sound, fat-free mass and handgrip strength (p < 0.05). Age-dependent decline in the total testosterone level was significantly associated with an increase in body fat percentage among the elderly men (p < 0.05). Conclusion: Testosterone levels are associated with changes in outcome of aging such as bone health status, muscle strength and body composition, and the relationships are age-dependent.

Original languageEnglish
Pages (from-to)240-245
Number of pages6
JournalAging Male
Volume15
Issue number4
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Muscle Strength
Body Composition
Health Status
Testosterone
Bone and Bones
Adipose Tissue
Fats
Sex Hormone-Binding Globulin
Linear Models
Regression Analysis

Keywords

  • Body composition
  • Calcaneal speed of sound
  • Handgrip strength
  • Men
  • Testosterone

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

@article{24d1ed64929d490d8876b9802a51f6e8,
title = "Testosterone is associated with age-related changes in bone health status, muscle strength and body composition in men",
abstract = "Objective: Variations in testosterone levels are associated with several outcomes of aging. The present study aimed to examine the relationship between age-related decline of testosterone levels and changes in bone health status, handgrip strength, body fat percentage and fat-free mass. Materials and methods: A total of 335 Malaysian Chinese and Malay men aged 40 years and above were recruited for this study. Their body compositions, calcaneal speed of sound and handgrip strength were measured and their blood was collected. Linear regression analysis was done to examine the relationship among age, testosterone levels and outcomes of aging. Results: The results indicated significant changes in all testosterone measurements, sex hormone binding globulin level, calcaneal speed of sound, handgrip strength, body fat percentage and fat-free mass with age (p < 0.05). Age-dependent decline in bioavailable and free testosterone levels were significantly associated with reduction in calcaneal speed of sound, fat-free mass and handgrip strength (p < 0.05). Age-dependent decline in the total testosterone level was significantly associated with an increase in body fat percentage among the elderly men (p < 0.05). Conclusion: Testosterone levels are associated with changes in outcome of aging such as bone health status, muscle strength and body composition, and the relationships are age-dependent.",
keywords = "Body composition, Calcaneal speed of sound, Handgrip strength, Men, Testosterone",
author = "{Kok Yong}, Chin and Soelaiman, {Ima Nirwana} and {Naina Mohamed}, Isa and Suzana Shahar and Teng, {Nur Islami Mohd Fahmi} and {Mohd Ramli}, {Elvy Suhana} and Fairus Ahmad and Amilia Aminuddin and Ngah, {Wan Zurinah Wan}",
year = "2012",
month = "12",
doi = "10.3109/13685538.2012.724740",
language = "English",
volume = "15",
pages = "240--245",
journal = "Aging Male",
issn = "1368-5538",
publisher = "Informa Healthcare",
number = "4",

}

TY - JOUR

T1 - Testosterone is associated with age-related changes in bone health status, muscle strength and body composition in men

AU - Kok Yong, Chin

AU - Soelaiman, Ima Nirwana

AU - Naina Mohamed, Isa

AU - Shahar, Suzana

AU - Teng, Nur Islami Mohd Fahmi

AU - Mohd Ramli, Elvy Suhana

AU - Ahmad, Fairus

AU - Aminuddin, Amilia

AU - Ngah, Wan Zurinah Wan

PY - 2012/12

Y1 - 2012/12

N2 - Objective: Variations in testosterone levels are associated with several outcomes of aging. The present study aimed to examine the relationship between age-related decline of testosterone levels and changes in bone health status, handgrip strength, body fat percentage and fat-free mass. Materials and methods: A total of 335 Malaysian Chinese and Malay men aged 40 years and above were recruited for this study. Their body compositions, calcaneal speed of sound and handgrip strength were measured and their blood was collected. Linear regression analysis was done to examine the relationship among age, testosterone levels and outcomes of aging. Results: The results indicated significant changes in all testosterone measurements, sex hormone binding globulin level, calcaneal speed of sound, handgrip strength, body fat percentage and fat-free mass with age (p < 0.05). Age-dependent decline in bioavailable and free testosterone levels were significantly associated with reduction in calcaneal speed of sound, fat-free mass and handgrip strength (p < 0.05). Age-dependent decline in the total testosterone level was significantly associated with an increase in body fat percentage among the elderly men (p < 0.05). Conclusion: Testosterone levels are associated with changes in outcome of aging such as bone health status, muscle strength and body composition, and the relationships are age-dependent.

AB - Objective: Variations in testosterone levels are associated with several outcomes of aging. The present study aimed to examine the relationship between age-related decline of testosterone levels and changes in bone health status, handgrip strength, body fat percentage and fat-free mass. Materials and methods: A total of 335 Malaysian Chinese and Malay men aged 40 years and above were recruited for this study. Their body compositions, calcaneal speed of sound and handgrip strength were measured and their blood was collected. Linear regression analysis was done to examine the relationship among age, testosterone levels and outcomes of aging. Results: The results indicated significant changes in all testosterone measurements, sex hormone binding globulin level, calcaneal speed of sound, handgrip strength, body fat percentage and fat-free mass with age (p < 0.05). Age-dependent decline in bioavailable and free testosterone levels were significantly associated with reduction in calcaneal speed of sound, fat-free mass and handgrip strength (p < 0.05). Age-dependent decline in the total testosterone level was significantly associated with an increase in body fat percentage among the elderly men (p < 0.05). Conclusion: Testosterone levels are associated with changes in outcome of aging such as bone health status, muscle strength and body composition, and the relationships are age-dependent.

KW - Body composition

KW - Calcaneal speed of sound

KW - Handgrip strength

KW - Men

KW - Testosterone

UR - http://www.scopus.com/inward/record.url?scp=84869797749&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869797749&partnerID=8YFLogxK

U2 - 10.3109/13685538.2012.724740

DO - 10.3109/13685538.2012.724740

M3 - Article

C2 - 23098182

AN - SCOPUS:84869797749

VL - 15

SP - 240

EP - 245

JO - Aging Male

JF - Aging Male

SN - 1368-5538

IS - 4

ER -