Tensile strength and bonding in compacts

A comparison of diametral compression and three-point bending for plastically deforming materials

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The tensile strength of tablets is frequently used as a measure of the bonding achieved during compaction. Tablets from two plastically deforming materials and one brittle material have been subjected to tensile strength testing using diametral compression and three-point bending. The plastically deforming materials exhibited marked inhomogeneities, with the surfaces of the tablets considerably more compact than the inner material. The results from the two tests were different, with the three-point bending test giving higher results for tensile strength. The rate of change of tensile strength with overall tablet porosity was, however, the same for the two tests. Diametral compression would thus appear to give a reasonable estimate of bonding despite the non-homogenous nature of tablets prepared from plastically deforming materials.

Original languageEnglish
Pages (from-to)809-813
Number of pages5
JournalDrug Development and Industrial Pharmacy
Volume28
Issue number7
DOIs
Publication statusPublished - 2002
Externally publishedYes

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Tensile Strength
Tablets
Compaction
Tensile strength
Porosity
Bending tests
Brittleness
Testing

Keywords

  • Bonding
  • Diametral compression
  • Tensile strength
  • Three-point bending

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Pharmacology
  • Molecular Medicine

Cite this

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abstract = "The tensile strength of tablets is frequently used as a measure of the bonding achieved during compaction. Tablets from two plastically deforming materials and one brittle material have been subjected to tensile strength testing using diametral compression and three-point bending. The plastically deforming materials exhibited marked inhomogeneities, with the surfaces of the tablets considerably more compact than the inner material. The results from the two tests were different, with the three-point bending test giving higher results for tensile strength. The rate of change of tensile strength with overall tablet porosity was, however, the same for the two tests. Diametral compression would thus appear to give a reasonable estimate of bonding despite the non-homogenous nature of tablets prepared from plastically deforming materials.",
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AB - The tensile strength of tablets is frequently used as a measure of the bonding achieved during compaction. Tablets from two plastically deforming materials and one brittle material have been subjected to tensile strength testing using diametral compression and three-point bending. The plastically deforming materials exhibited marked inhomogeneities, with the surfaces of the tablets considerably more compact than the inner material. The results from the two tests were different, with the three-point bending test giving higher results for tensile strength. The rate of change of tensile strength with overall tablet porosity was, however, the same for the two tests. Diametral compression would thus appear to give a reasonable estimate of bonding despite the non-homogenous nature of tablets prepared from plastically deforming materials.

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