Synthetic antibody

Prospects in aquaculture biosecurity

Chou Min Chong, Low Chen Fei

Research output: Contribution to journalReview article

Abstract

The emerging technology of aptamers that is also known as synthetic antibodies is rivalling antibodies research in the recent years. The unique yet important features of aptamers are advancing antibodies in diverse applications, which include disease diagnosis, prophylactic and therapeutic. The versatility of aptamer has further extended its application to function as gene expression modulator, known as synthetic riboswitches. This report reviewed and discussed the applications of aptamers technology in the biosecurity of aquaculture, the promising developments in biosensor detection for disease diagnosis as well as prophylactic and therapeutic measurements. The application of aptamers technology in immunophenotyping study of aquatic animal is highlighted. Lastly, the future perspective of aptamers in the management of aquatic animal health is discussed, special emphasis on the potential application of aptamers as synthetic riboswitches to enhance host immunity, as well as the growth performance.

Original languageEnglish
Pages (from-to)361-367
Number of pages7
JournalFish and Shellfish Immunology
Volume86
DOIs
Publication statusPublished - 1 Mar 2019

Fingerprint

Aquaculture
biosecurity
antibody
aquaculture
application technology
disease diagnosis
Riboswitch
antibodies
Antibodies
therapeutics
biosensors
immunity
Animals
animal health
gene expression
growth performance
Gene expression
Biosensors
Modulators
Health

Keywords

  • Aptamers
  • Disease diagnosis
  • Immunophenotyping
  • Prophylactic
  • Synthetic antibody
  • Synthetic riboswitches
  • Therapeutic

ASJC Scopus subject areas

  • Environmental Chemistry
  • Aquatic Science

Cite this

Synthetic antibody : Prospects in aquaculture biosecurity. / Chong, Chou Min; Chen Fei, Low.

In: Fish and Shellfish Immunology, Vol. 86, 01.03.2019, p. 361-367.

Research output: Contribution to journalReview article

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