Synthesis of new polymers derived from poly (vinyl chloride) and study their biological evaluation

Emad Yousif, Ayad Hameed, Adel Kamil, Yang Farina Abdul Aziz, Noora Asaad, Abdualbasit Graisa

Research output: Contribution to journalArticle

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Abstract

Poly(vinyl chloride) (PVC) was modified with phthalyl and 1,3,4-thiadiazole binding units in a three steps reaction. First, five phthaloyl amino acids [1-5] was prepared by heating a mixture of finely grounded phthalic anhydride and appropriate amino acid. Second, Reaction of compounds [1-5] with thiosemicarbazide in the presence of POCl 3 afforded five new 1,3,4-thiadiazole compounds [6-10].Third, Five modified PVC-polymers containing 1,3,4-thiadiazole and phthalyl groups in the repeating units were synthesized through the reaction of compounds [6-10] with PVC in THF solvent. Finally, the structures of the all synthesized compounds were characterized by spectral (IR and UV) analysis, CHNS, melting point for organic compounds and softening point for polymers; the results indicated the expected structures of these compounds. The prepared compounds were tested for their antimicrobial activities.

Original languageEnglish
Pages (from-to)1786-1794
Number of pages9
JournalAustralian Journal of Basic and Applied Sciences
Volume3
Issue number3
Publication statusPublished - Jul 2009

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Vinyl Chloride
Polyvinyl Chloride
Polymers
Amino Acids
Organic compounds
Melting point
Heating
1,3,4-thiadiazole

Keywords

  • 1,3,4-thiadiazole
  • Biological activity
  • Poly(vinyl chloride)
  • Spectral studies

ASJC Scopus subject areas

  • General

Cite this

Synthesis of new polymers derived from poly (vinyl chloride) and study their biological evaluation. / Yousif, Emad; Hameed, Ayad; Kamil, Adel; Abdul Aziz, Yang Farina; Asaad, Noora; Graisa, Abdualbasit.

In: Australian Journal of Basic and Applied Sciences, Vol. 3, No. 3, 07.2009, p. 1786-1794.

Research output: Contribution to journalArticle

Yousif, Emad ; Hameed, Ayad ; Kamil, Adel ; Abdul Aziz, Yang Farina ; Asaad, Noora ; Graisa, Abdualbasit. / Synthesis of new polymers derived from poly (vinyl chloride) and study their biological evaluation. In: Australian Journal of Basic and Applied Sciences. 2009 ; Vol. 3, No. 3. pp. 1786-1794.
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