Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution

S. A. Syed Nuzul Fadzli, Roslinda Shamsudin, Firuz Zainuddin

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

The objective of this study is to determine the bioactive property of compacted and crystallized glass-ceramic based on 60 (wt.)%SiO2-40 (wt.)%CaO by immersion in simulated body fluid (SBF) for various times. The powder of this phosphate-free glasses based on binary SiO2-CaO system was synthesized via an acid catalyzed sol-gel route prior to powder compaction for the bioactivity assessment. The main chemical precursors used for synthesis the glass powder were tetraethylorthosilicate (TEOS) and calcium nitrate tetrahydrate reagent whereas nitric acid was used as the catalyst during the sol-gel process. The obtained hydrogels were dried, heat treated and grounded into powders before being pressed into rounded shape compacts. The initial compacted glass then sintered at 1000°C for 4 hours in typical muffle furnace to obtain crystallized glassceramic phase. Precipitation of apatite structures on the glass-ceramic surface were observed by immersion of the compacted pellets into SBF solution from one to 21 days. All the test results obtained from X-Ray Diffraction (XRD), Fourier Transform-Infrared (FT-IR), Field EmissionScanning Electron Microscopy (FE-SEM) and Energy Dispersive Spectroscopy (EDS) indicates that the sintered glass-ceramic showed an actively bioactivity property. Precipitation of apatite was detected on the surface of the compacted glass-ceramic within the first 24 hours after being immersed in SBF. The development of apatite structures were continuously increased and progressively growth into coral-like structure and has particularly found to crystallize into carbonated apatite (HCA) layer after 14 days of immersion in SBF.

Original languageEnglish
Title of host publicationKey Engineering Materials
PublisherTrans Tech Publications Ltd
Pages161-170
Number of pages10
Volume673
DOIs
Publication statusPublished - 2016

Publication series

NameKey Engineering Materials
Volume673
ISSN (Print)10139826

Fingerprint

Apatites
Body fluids
Apatite
Glass ceramics
Bioactivity
Powders
Sol-gels
Glass
Nitric Acid
Hydrogels
Nitric acid
Sol-gel process
Electron microscopy
Energy dispersive spectroscopy
Calcium
Nitrates
Fourier transforms
Phosphates
Furnaces
Compaction

Keywords

  • Bioactive glass
  • Biomaterial
  • Composite
  • Glass
  • Silica-based xerogels
  • Sol-gel

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Syed Nuzul Fadzli, S. A., Shamsudin, R., & Zainuddin, F. (2016). Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution. In Key Engineering Materials (Vol. 673, pp. 161-170). (Key Engineering Materials; Vol. 673). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.673.161

Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution. / Syed Nuzul Fadzli, S. A.; Shamsudin, Roslinda; Zainuddin, Firuz.

Key Engineering Materials. Vol. 673 Trans Tech Publications Ltd, 2016. p. 161-170 (Key Engineering Materials; Vol. 673).

Research output: Chapter in Book/Report/Conference proceedingChapter

Syed Nuzul Fadzli, SA, Shamsudin, R & Zainuddin, F 2016, Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution. in Key Engineering Materials. vol. 673, Key Engineering Materials, vol. 673, Trans Tech Publications Ltd, pp. 161-170. https://doi.org/10.4028/www.scientific.net/KEM.673.161
Syed Nuzul Fadzli SA, Shamsudin R, Zainuddin F. Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution. In Key Engineering Materials. Vol. 673. Trans Tech Publications Ltd. 2016. p. 161-170. (Key Engineering Materials). https://doi.org/10.4028/www.scientific.net/KEM.673.161
Syed Nuzul Fadzli, S. A. ; Shamsudin, Roslinda ; Zainuddin, Firuz. / Synthesis of 60 (wt.)%SiO2-40 (wt.)%CaO sol-gel derived glass-ceramic and in vitro bioactivity assessment in SBF solution. Key Engineering Materials. Vol. 673 Trans Tech Publications Ltd, 2016. pp. 161-170 (Key Engineering Materials).
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abstract = "The objective of this study is to determine the bioactive property of compacted and crystallized glass-ceramic based on 60 (wt.){\%}SiO2-40 (wt.){\%}CaO by immersion in simulated body fluid (SBF) for various times. The powder of this phosphate-free glasses based on binary SiO2-CaO system was synthesized via an acid catalyzed sol-gel route prior to powder compaction for the bioactivity assessment. The main chemical precursors used for synthesis the glass powder were tetraethylorthosilicate (TEOS) and calcium nitrate tetrahydrate reagent whereas nitric acid was used as the catalyst during the sol-gel process. The obtained hydrogels were dried, heat treated and grounded into powders before being pressed into rounded shape compacts. The initial compacted glass then sintered at 1000°C for 4 hours in typical muffle furnace to obtain crystallized glassceramic phase. Precipitation of apatite structures on the glass-ceramic surface were observed by immersion of the compacted pellets into SBF solution from one to 21 days. All the test results obtained from X-Ray Diffraction (XRD), Fourier Transform-Infrared (FT-IR), Field EmissionScanning Electron Microscopy (FE-SEM) and Energy Dispersive Spectroscopy (EDS) indicates that the sintered glass-ceramic showed an actively bioactivity property. Precipitation of apatite was detected on the surface of the compacted glass-ceramic within the first 24 hours after being immersed in SBF. The development of apatite structures were continuously increased and progressively growth into coral-like structure and has particularly found to crystallize into carbonated apatite (HCA) layer after 14 days of immersion in SBF.",
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