Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene

Hamza M. Abosadiya, Siti Aishah Hasbullah, Bohari Mohd. Yamin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

C-4-acetamidophenylcalix[4]pyrogallolarene was synthesized by an acid catalyzed condensation reaction of pyrogallol with 4-acetamidobenzaldehyde. The compound was characterized by IR, 1H and 13C NMR spectroscopy. Single crystal X-ray analysis revealed that the molecule crystallized in a triclinic system with space group Pi¯ and the unit cell dimensions a= 12.2948(16) Å, b= 13.4423(17) Å, c= 13.5906(18) Å, α =107.549(4)°, β =102.034(4)°, γ =90.535(4)°, Z= 1 and V= 2088.2(5) Å3. The macrocyclic calix adopts a chair (C2h) conformation and the molecule is associated with eight DMSO molecules of crystallization. Antioxidant test by DPPH method showed that the compound exhibits good antioxidant activity of about 72%.

Original languageEnglish
Title of host publication2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1678
ISBN (Electronic)9780735413252
DOIs
Publication statusPublished - 25 Sep 2015
Event2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015 - Selangor, Malaysia
Duration: 15 Apr 201516 Apr 2015

Other

Other2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015
CountryMalaysia
CitySelangor
Period15/4/1516/4/15

Fingerprint

antioxidants
crystal structure
evaluation
synthesis
molecules
seats
condensation
crystallization
nuclear magnetic resonance
acids
single crystals
cells
spectroscopy
x rays

Keywords

  • C-4-acetamidophenylcalix[4]pyrogallolarene
  • X-ray structural

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Abosadiya, H. M., Hasbullah, S. A., & Mohd. Yamin, B. (2015). Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium (Vol. 1678). [050024] American Institute of Physics Inc.. https://doi.org/10.1063/1.4931303

Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene. / Abosadiya, Hamza M.; Hasbullah, Siti Aishah; Mohd. Yamin, Bohari.

2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015. 050024.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abosadiya, HM, Hasbullah, SA & Mohd. Yamin, B 2015, Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene. in 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. vol. 1678, 050024, American Institute of Physics Inc., 2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015, Selangor, Malaysia, 15/4/15. https://doi.org/10.1063/1.4931303
Abosadiya HM, Hasbullah SA, Mohd. Yamin B. Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678. American Institute of Physics Inc. 2015. 050024 https://doi.org/10.1063/1.4931303
Abosadiya, Hamza M. ; Hasbullah, Siti Aishah ; Mohd. Yamin, Bohari. / Synthesis, crystal structure and antioxidant evaluation of C -4-acetamidophenylcalix[4]pyrogallolarene. 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015.
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abstract = "C-4-acetamidophenylcalix[4]pyrogallolarene was synthesized by an acid catalyzed condensation reaction of pyrogallol with 4-acetamidobenzaldehyde. The compound was characterized by IR, 1H and 13C NMR spectroscopy. Single crystal X-ray analysis revealed that the molecule crystallized in a triclinic system with space group Pi¯ and the unit cell dimensions a= 12.2948(16) {\AA}, b= 13.4423(17) {\AA}, c= 13.5906(18) {\AA}, α =107.549(4)°, β =102.034(4)°, γ =90.535(4)°, Z= 1 and V= 2088.2(5) {\AA}3. The macrocyclic calix adopts a chair (C2h) conformation and the molecule is associated with eight DMSO molecules of crystallization. Antioxidant test by DPPH method showed that the compound exhibits good antioxidant activity of about 72{\%}.",
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N2 - C-4-acetamidophenylcalix[4]pyrogallolarene was synthesized by an acid catalyzed condensation reaction of pyrogallol with 4-acetamidobenzaldehyde. The compound was characterized by IR, 1H and 13C NMR spectroscopy. Single crystal X-ray analysis revealed that the molecule crystallized in a triclinic system with space group Pi¯ and the unit cell dimensions a= 12.2948(16) Å, b= 13.4423(17) Å, c= 13.5906(18) Å, α =107.549(4)°, β =102.034(4)°, γ =90.535(4)°, Z= 1 and V= 2088.2(5) Å3. The macrocyclic calix adopts a chair (C2h) conformation and the molecule is associated with eight DMSO molecules of crystallization. Antioxidant test by DPPH method showed that the compound exhibits good antioxidant activity of about 72%.

AB - C-4-acetamidophenylcalix[4]pyrogallolarene was synthesized by an acid catalyzed condensation reaction of pyrogallol with 4-acetamidobenzaldehyde. The compound was characterized by IR, 1H and 13C NMR spectroscopy. Single crystal X-ray analysis revealed that the molecule crystallized in a triclinic system with space group Pi¯ and the unit cell dimensions a= 12.2948(16) Å, b= 13.4423(17) Å, c= 13.5906(18) Å, α =107.549(4)°, β =102.034(4)°, γ =90.535(4)°, Z= 1 and V= 2088.2(5) Å3. The macrocyclic calix adopts a chair (C2h) conformation and the molecule is associated with eight DMSO molecules of crystallization. Antioxidant test by DPPH method showed that the compound exhibits good antioxidant activity of about 72%.

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