Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine was synthesized from 2-chlorobenzoylisothiocyanate and hydrazine in acetone. The compound was characterized by infrared, 1H and 13C NMR, and UV-Vis spectroscopies. X-ray crystallography study showed the molecule adopt trans configuration at both N-N and C-N bonds. The compound showed high antioxidant activity, EC50 of 374.89 μM, compared to ascorbic acid (EC50 of 561.36 μM).

Original languageEnglish
Title of host publication2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1678
ISBN (Electronic)9780735413252
DOIs
Publication statusPublished - 25 Sep 2015
Event2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015 - Selangor, Malaysia
Duration: 15 Apr 201516 Apr 2015

Other

Other2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015
CountryMalaysia
CitySelangor
Period15/4/1516/4/15

Fingerprint

antioxidants
hydrazines
ascorbic acid
synthesis
acetone
crystallography
nuclear magnetic resonance
configurations
spectroscopy
molecules
x rays

Keywords

  • Antioxidant activity
  • Bis-thiourea
  • X-ray crystallography

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Firdausiah, S., Hasbullah, S. A., & Mohd. Yamin, B. (2015). Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium (Vol. 1678). [050035] American Institute of Physics Inc.. https://doi.org/10.1063/1.4931314

Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine. / Firdausiah, Syadza; Hasbullah, Siti Aishah; Mohd. Yamin, Bohari.

2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015. 050035.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Firdausiah, S, Hasbullah, SA & Mohd. Yamin, B 2015, Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine. in 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. vol. 1678, 050035, American Institute of Physics Inc., 2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015, Selangor, Malaysia, 15/4/15. https://doi.org/10.1063/1.4931314
Firdausiah S, Hasbullah SA, Mohd. Yamin B. Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine. In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678. American Institute of Physics Inc. 2015. 050035 https://doi.org/10.1063/1.4931314
Firdausiah, Syadza ; Hasbullah, Siti Aishah ; Mohd. Yamin, Bohari. / Synthesis, characterization and antioxidant study of N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine. 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015.
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abstract = "N,N'-bis(2-chlorobenzamidothiocarbonyl)hydrazine was synthesized from 2-chlorobenzoylisothiocyanate and hydrazine in acetone. The compound was characterized by infrared, 1H and 13C NMR, and UV-Vis spectroscopies. X-ray crystallography study showed the molecule adopt trans configuration at both N-N and C-N bonds. The compound showed high antioxidant activity, EC50 of 374.89 μM, compared to ascorbic acid (EC50 of 561.36 μM).",
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