Synthesis, characterization and antimicrobial evaluation of some 1,3,4-oxadiazole derivatives

Nadia Salih, Jumat Salimon, Ayad Hameed, Emad Yousif

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In the present study a series of new 1,3,4-oxadiazole derivatives were synthesized. These newly synthesized compounds were characterized by NMR, mass spectral, IR spectral study and also by C, H, N analyses. All the newly synthesized compounds were screened for their antibacterial and antifungal studies. Antimicrobial studies revealed that compounds 6 showed significant antibacterial activity against Candida albicans. Compound 7 showed significant antifungal activity against Escherichia coli and Pseudomonas aeruginosa.

Original languageEnglish
Pages (from-to)1097-1102
Number of pages6
JournalInternational Journal of PharmTech Research
Volume3
Issue number2
Publication statusPublished - 2011

Fingerprint

Candida albicans
Pseudomonas aeruginosa
Escherichia coli
1,3,4-oxadiazole

Keywords

  • 1,3,4-oxadiazole
  • Antibacterial study
  • Antifungal study

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

Cite this

Synthesis, characterization and antimicrobial evaluation of some 1,3,4-oxadiazole derivatives. / Salih, Nadia; Salimon, Jumat; Hameed, Ayad; Yousif, Emad.

In: International Journal of PharmTech Research, Vol. 3, No. 2, 2011, p. 1097-1102.

Research output: Contribution to journalArticle

Salih, Nadia ; Salimon, Jumat ; Hameed, Ayad ; Yousif, Emad. / Synthesis, characterization and antimicrobial evaluation of some 1,3,4-oxadiazole derivatives. In: International Journal of PharmTech Research. 2011 ; Vol. 3, No. 2. pp. 1097-1102.
@article{72189f88464043e9a6b959477de74c7f,
title = "Synthesis, characterization and antimicrobial evaluation of some 1,3,4-oxadiazole derivatives",
abstract = "In the present study a series of new 1,3,4-oxadiazole derivatives were synthesized. These newly synthesized compounds were characterized by NMR, mass spectral, IR spectral study and also by C, H, N analyses. All the newly synthesized compounds were screened for their antibacterial and antifungal studies. Antimicrobial studies revealed that compounds 6 showed significant antibacterial activity against Candida albicans. Compound 7 showed significant antifungal activity against Escherichia coli and Pseudomonas aeruginosa.",
keywords = "1,3,4-oxadiazole, Antibacterial study, Antifungal study",
author = "Nadia Salih and Jumat Salimon and Ayad Hameed and Emad Yousif",
year = "2011",
language = "English",
volume = "3",
pages = "1097--1102",
journal = "International Journal of PharmTech Research",
issn = "0974-4304",
publisher = "Sphinx Knowledge House",
number = "2",

}

TY - JOUR

T1 - Synthesis, characterization and antimicrobial evaluation of some 1,3,4-oxadiazole derivatives

AU - Salih, Nadia

AU - Salimon, Jumat

AU - Hameed, Ayad

AU - Yousif, Emad

PY - 2011

Y1 - 2011

N2 - In the present study a series of new 1,3,4-oxadiazole derivatives were synthesized. These newly synthesized compounds were characterized by NMR, mass spectral, IR spectral study and also by C, H, N analyses. All the newly synthesized compounds were screened for their antibacterial and antifungal studies. Antimicrobial studies revealed that compounds 6 showed significant antibacterial activity against Candida albicans. Compound 7 showed significant antifungal activity against Escherichia coli and Pseudomonas aeruginosa.

AB - In the present study a series of new 1,3,4-oxadiazole derivatives were synthesized. These newly synthesized compounds were characterized by NMR, mass spectral, IR spectral study and also by C, H, N analyses. All the newly synthesized compounds were screened for their antibacterial and antifungal studies. Antimicrobial studies revealed that compounds 6 showed significant antibacterial activity against Candida albicans. Compound 7 showed significant antifungal activity against Escherichia coli and Pseudomonas aeruginosa.

KW - 1,3,4-oxadiazole

KW - Antibacterial study

KW - Antifungal study

UR - http://www.scopus.com/inward/record.url?scp=84856280444&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84856280444&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84856280444

VL - 3

SP - 1097

EP - 1102

JO - International Journal of PharmTech Research

JF - International Journal of PharmTech Research

SN - 0974-4304

IS - 2

ER -