Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine

Dalina Adan, Bohari Mohd. Yamin, Ong Wei Leng, Nazlina Ibrahim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A new tripodal tris-(N-benzoylthiouredoethyl)amine has been successfully synthesized and characterized by spectroscopic technique such as FTIR, ESI MS, 1 H and 13 C NMR. The microanalysis data is in a good agreement with the expected molecular formula. The 1 H NMR chemical shift for both amide and thioamide proton are at lower field than their normal value indicates the presence of the hydrogen bond between the carbonyl oxygen atom and thioamide hydrogen. This is possible when the benzoyl group adopt a trans configuration againts thione group along the C-N bond. The compound has been tested for antibacterial activity against three selected bacteria namely Staphylococcus aureus, Proteus vulgaris and Pseudomanas aeroginosa but there is no significant activities observed.

Original languageEnglish
Title of host publication2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium
EditorsZahari Ibrahim, Haja Maideen Kader Maideen, Nazlina Ibrahim, Nurul Huda Abd Karim, Taufik Yusof, Fatimah Abdul Razak, Nurulkamal Maseran, Rozida Mohd Khalid, Noor Baa'yah Ibrahim, Hasidah Mohd. Sidek, Mohd Salmi Md Noorani, Norbert Simon
PublisherAmerican Institute of Physics Inc.
Pages218-223
Number of pages6
ISBN (Electronic)9780735412507
DOIs
Publication statusPublished - 1 Jan 2014
Event2014 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2014 - Selangor, Malaysia
Duration: 9 Apr 201411 Apr 2014

Publication series

NameAIP Conference Proceedings
Volume1614
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other2014 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2014
CountryMalaysia
CitySelangor
Period9/4/1411/4/14

Fingerprint

Proteus
nuclear magnetic resonance
staphylococcus
synthesis
microanalysis
bacteria
amides
chemical equilibrium
oxygen atoms
amines
hydrogen bonds
protons
hydrogen
configurations

Keywords

  • Antibacterial activity
  • Hydrogen bond
  • Spectroscopy
  • Tris-(n-benzoylthioureidoethyl)amine

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Adan, D., Mohd. Yamin, B., Leng, O. W., & Ibrahim, N. (2014). Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine. In Z. Ibrahim, H. M. K. Maideen, N. Ibrahim, N. H. A. Karim, T. Yusof, F. A. Razak, N. Maseran, R. M. Khalid, N. B. Ibrahim, H. M. Sidek, M. S. M. Noorani, ... N. Simon (Eds.), 2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium (pp. 218-223). (AIP Conference Proceedings; Vol. 1614). American Institute of Physics Inc.. https://doi.org/10.1063/1.4895199

Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine. / Adan, Dalina; Mohd. Yamin, Bohari; Leng, Ong Wei; Ibrahim, Nazlina.

2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. ed. / Zahari Ibrahim; Haja Maideen Kader Maideen; Nazlina Ibrahim; Nurul Huda Abd Karim; Taufik Yusof; Fatimah Abdul Razak; Nurulkamal Maseran; Rozida Mohd Khalid; Noor Baa'yah Ibrahim; Hasidah Mohd. Sidek; Mohd Salmi Md Noorani; Norbert Simon. American Institute of Physics Inc., 2014. p. 218-223 (AIP Conference Proceedings; Vol. 1614).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Adan, D, Mohd. Yamin, B, Leng, OW & Ibrahim, N 2014, Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine. in Z Ibrahim, HMK Maideen, N Ibrahim, NHA Karim, T Yusof, FA Razak, N Maseran, RM Khalid, NB Ibrahim, HM Sidek, MSM Noorani & N Simon (eds), 2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. AIP Conference Proceedings, vol. 1614, American Institute of Physics Inc., pp. 218-223, 2014 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2014, Selangor, Malaysia, 9/4/14. https://doi.org/10.1063/1.4895199
Adan D, Mohd. Yamin B, Leng OW, Ibrahim N. Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine. In Ibrahim Z, Maideen HMK, Ibrahim N, Karim NHA, Yusof T, Razak FA, Maseran N, Khalid RM, Ibrahim NB, Sidek HM, Noorani MSM, Simon N, editors, 2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. American Institute of Physics Inc. 2014. p. 218-223. (AIP Conference Proceedings). https://doi.org/10.1063/1.4895199
Adan, Dalina ; Mohd. Yamin, Bohari ; Leng, Ong Wei ; Ibrahim, Nazlina. / Synthesis, characterization and antibacterial study of tripodal tris-(N-benzoylthioureido)ethylamine. 2014 UKM FST Postgraduate Colloquium - Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2014 Postgraduate Colloquium. editor / Zahari Ibrahim ; Haja Maideen Kader Maideen ; Nazlina Ibrahim ; Nurul Huda Abd Karim ; Taufik Yusof ; Fatimah Abdul Razak ; Nurulkamal Maseran ; Rozida Mohd Khalid ; Noor Baa'yah Ibrahim ; Hasidah Mohd. Sidek ; Mohd Salmi Md Noorani ; Norbert Simon. American Institute of Physics Inc., 2014. pp. 218-223 (AIP Conference Proceedings).
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