Synthesis and optimization of acrylic-N-acryloxysuccinimide copolymer microspheres

Alizar Ulianas, Nurlely, Yulkifli, Yook Heng Lee, Ling Ling Tan @ Chong

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A micro-sized poly(n-butyl acrylate-co-N-acryloxysuccinimide) [poly(nBA-co-NAS] copolymer bio-carrier matrix has been synthesized from n-butyl acrylate (nBA) and N-acryloxysuccinimide (NAS) monomers through a single step emulsion photopolymerization protocol. Narrower size distribution of the copolymer microspheres having a size in the range of 0.31-1.04 μm was obtained using nBA-SDS composition ratio of 0.25:5.00 (mL: mg). The FTIR analysis result confirmed the presence of the useful succinimide functional groups on the poly(nBA-co-NAS), which rendered the copolymer microspheres a feasible alternative to other polymers for use as biological immobilization carrier for enzymes and DNA molecules in the fabrication of advanced biosensor devices. The low glass transition temperature (Tg) of the as-synthesized copolymer microspheres signifies the soft and good adhesion properties of the matrix to be attached to the solid support to form the miniature solid-state biosensing devices.

Original languageEnglish
Pages (from-to)780-784
Number of pages5
JournalInternational Journal on Advanced Science, Engineering and Information Technology
Volume8
Issue number3
Publication statusPublished - 1 Jan 2018

Fingerprint

composite polymers
Microspheres
Acrylics
Copolymers
synthesis
Equipment and Supplies
Transition Temperature
Biosensing Techniques
Fourier Transform Infrared Spectroscopy
Emulsions
Solid state devices
Immobilization
Glass
Photopolymerization
Polymers
Biosensors
glass transition temperature
Functional groups
biosensors
DNA

Keywords

  • Copolymer
  • Immobilization matrix
  • Microspheres
  • Photo-polymerization

ASJC Scopus subject areas

  • Computer Science(all)
  • Agricultural and Biological Sciences(all)
  • Engineering(all)

Cite this

Synthesis and optimization of acrylic-N-acryloxysuccinimide copolymer microspheres. / Ulianas, Alizar; Nurlely; Yulkifli, ; Lee, Yook Heng; Tan @ Chong, Ling Ling.

In: International Journal on Advanced Science, Engineering and Information Technology, Vol. 8, No. 3, 01.01.2018, p. 780-784.

Research output: Contribution to journalArticle

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