Synthesis and characterization of some diorganotin(IV) complexes of 2,3-dihydroxybenzaldehyde N(4)-substituted thiosemicarbazone

Abdurazag T. Swesi, Yang Farina Abdul Aziz, Ibrahim Baba

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Organotin compounds especially the dialkyltin derivatives are reported to possess anti-tumour properties. The diorganotin(IV) complexes of the type Me2SnL1, Me2SnL2, Bu2SnL1, Bu2SnL2 and Ph2SnL1 (L1 and L2 is the anion of the thiosemicarbazone ligand formed by the condensation reaction of 2,3-dihydroxybenzaldehyde with thiosemicarbazide or its N(4)-methyl substituent) were synthesized using 1:1 metal-to-ligand reactant ratios. The newly synthesized complexes were characterized using elemental analysis, infrared and nuclear magnetic resonance (1H, 13C, 119Sn) spectroscopic techniques. Complex formation between the organotin(IV) moiety and the anions of 2,3-dihydroxybenzaldehyde thiosemicarbazone and 2,3-dihydroxybenzaldehyde 4-methylthiosemicarbazone occurred with chelation at the o-dihydroxy positions. The complexes are proposed to have tetrahedral geometry.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalSains Malaysiana
Volume36
Issue number1
Publication statusPublished - Jul 2007

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Thiosemicarbazones
Anions
Organotin Compounds
Ligands
Condensation reactions
Chelation
Tumors
Metals
Nuclear magnetic resonance
Infrared radiation
Derivatives
Geometry
Chemical analysis
2,3-dihydroxybenzaldehyde

Keywords

  • Organotin
  • Synthesis
  • Thiosemicarbazones

ASJC Scopus subject areas

  • General

Cite this

Synthesis and characterization of some diorganotin(IV) complexes of 2,3-dihydroxybenzaldehyde N(4)-substituted thiosemicarbazone. / Swesi, Abdurazag T.; Abdul Aziz, Yang Farina; Baba, Ibrahim.

In: Sains Malaysiana, Vol. 36, No. 1, 07.2007, p. 21-26.

Research output: Contribution to journalArticle

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AU - Abdul Aziz, Yang Farina

AU - Baba, Ibrahim

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N2 - Organotin compounds especially the dialkyltin derivatives are reported to possess anti-tumour properties. The diorganotin(IV) complexes of the type Me2SnL1, Me2SnL2, Bu2SnL1, Bu2SnL2 and Ph2SnL1 (L1 and L2 is the anion of the thiosemicarbazone ligand formed by the condensation reaction of 2,3-dihydroxybenzaldehyde with thiosemicarbazide or its N(4)-methyl substituent) were synthesized using 1:1 metal-to-ligand reactant ratios. The newly synthesized complexes were characterized using elemental analysis, infrared and nuclear magnetic resonance (1H, 13C, 119Sn) spectroscopic techniques. Complex formation between the organotin(IV) moiety and the anions of 2,3-dihydroxybenzaldehyde thiosemicarbazone and 2,3-dihydroxybenzaldehyde 4-methylthiosemicarbazone occurred with chelation at the o-dihydroxy positions. The complexes are proposed to have tetrahedral geometry.

AB - Organotin compounds especially the dialkyltin derivatives are reported to possess anti-tumour properties. The diorganotin(IV) complexes of the type Me2SnL1, Me2SnL2, Bu2SnL1, Bu2SnL2 and Ph2SnL1 (L1 and L2 is the anion of the thiosemicarbazone ligand formed by the condensation reaction of 2,3-dihydroxybenzaldehyde with thiosemicarbazide or its N(4)-methyl substituent) were synthesized using 1:1 metal-to-ligand reactant ratios. The newly synthesized complexes were characterized using elemental analysis, infrared and nuclear magnetic resonance (1H, 13C, 119Sn) spectroscopic techniques. Complex formation between the organotin(IV) moiety and the anions of 2,3-dihydroxybenzaldehyde thiosemicarbazone and 2,3-dihydroxybenzaldehyde 4-methylthiosemicarbazone occurred with chelation at the o-dihydroxy positions. The complexes are proposed to have tetrahedral geometry.

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