Synthesis and characterization of novel diorganotin(IV) complexes derived from N-methyl-phenethyl dithiocarbamate and bis(2-ethoxyethyl) dithiocarbamate

Norraphat Uttraphan Pim, Normah Awang, Rapidah Mohamad, Yang Farina Abdul Aziz, Kamaludin Nurul Farahana

Research output: Contribution to journalArticle

Abstract

Organotin(IV) dithiocarbamate complexes are extensively studied worldwide as they have proven to exhibit promising anticancer, antimicrobial and larvicidal properties. In this study, three new organotin(IV) dithiocarbamate complexes have been successfully synthesized via in situ reaction between the appropriate secondary amines with carbon disulphide and organotin(IV) salts, in a basic solution at temperature below 4 °C. The complexes were characterized by CHNS elemental analysis, FTIR and 1H, 13C and 119Sn NMR. All complexes displayed the important NCS2 peak from 200.02-201.35 ppm in 13C NMR, signifying the presence of the dithiocarbamate ligand. The complexes also produced the essential IR bands, ?(C-N), ?(C-S) and ?(Sn-C) in the ranges 1489 to 1479 cm-1, 986.2 to 971.2 cm-1 and 568.2 to 550.8 cm-1, respectively. From the 119Sn NMR, both the ligands were suggested to coordinate to the tin atom in a bidentate manner in all three complexes.

Original languageEnglish
Pages (from-to)1364-1368
Number of pages5
JournalAsian Journal of Chemistry
Volume30
Issue number6
DOIs
Publication statusPublished - 1 Jan 2018

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Nuclear magnetic resonance
Carbon Disulfide
Ligands
Tin
Amines
Salts
Atoms
Chemical analysis
Temperature

Keywords

  • Anticancer
  • Dithiocarbamate
  • Nanoparticles.
  • Organotin(IV)

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

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title = "Synthesis and characterization of novel diorganotin(IV) complexes derived from N-methyl-phenethyl dithiocarbamate and bis(2-ethoxyethyl) dithiocarbamate",
abstract = "Organotin(IV) dithiocarbamate complexes are extensively studied worldwide as they have proven to exhibit promising anticancer, antimicrobial and larvicidal properties. In this study, three new organotin(IV) dithiocarbamate complexes have been successfully synthesized via in situ reaction between the appropriate secondary amines with carbon disulphide and organotin(IV) salts, in a basic solution at temperature below 4 °C. The complexes were characterized by CHNS elemental analysis, FTIR and 1H, 13C and 119Sn NMR. All complexes displayed the important NCS2 peak from 200.02-201.35 ppm in 13C NMR, signifying the presence of the dithiocarbamate ligand. The complexes also produced the essential IR bands, ?(C-N), ?(C-S) and ?(Sn-C) in the ranges 1489 to 1479 cm-1, 986.2 to 971.2 cm-1 and 568.2 to 550.8 cm-1, respectively. From the 119Sn NMR, both the ligands were suggested to coordinate to the tin atom in a bidentate manner in all three complexes.",
keywords = "Anticancer, Dithiocarbamate, Nanoparticles., Organotin(IV)",
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AU - Pim, Norraphat Uttraphan

AU - Awang, Normah

AU - Mohamad, Rapidah

AU - Abdul Aziz, Yang Farina

AU - Nurul Farahana, Kamaludin

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Organotin(IV) dithiocarbamate complexes are extensively studied worldwide as they have proven to exhibit promising anticancer, antimicrobial and larvicidal properties. In this study, three new organotin(IV) dithiocarbamate complexes have been successfully synthesized via in situ reaction between the appropriate secondary amines with carbon disulphide and organotin(IV) salts, in a basic solution at temperature below 4 °C. The complexes were characterized by CHNS elemental analysis, FTIR and 1H, 13C and 119Sn NMR. All complexes displayed the important NCS2 peak from 200.02-201.35 ppm in 13C NMR, signifying the presence of the dithiocarbamate ligand. The complexes also produced the essential IR bands, ?(C-N), ?(C-S) and ?(Sn-C) in the ranges 1489 to 1479 cm-1, 986.2 to 971.2 cm-1 and 568.2 to 550.8 cm-1, respectively. From the 119Sn NMR, both the ligands were suggested to coordinate to the tin atom in a bidentate manner in all three complexes.

AB - Organotin(IV) dithiocarbamate complexes are extensively studied worldwide as they have proven to exhibit promising anticancer, antimicrobial and larvicidal properties. In this study, three new organotin(IV) dithiocarbamate complexes have been successfully synthesized via in situ reaction between the appropriate secondary amines with carbon disulphide and organotin(IV) salts, in a basic solution at temperature below 4 °C. The complexes were characterized by CHNS elemental analysis, FTIR and 1H, 13C and 119Sn NMR. All complexes displayed the important NCS2 peak from 200.02-201.35 ppm in 13C NMR, signifying the presence of the dithiocarbamate ligand. The complexes also produced the essential IR bands, ?(C-N), ?(C-S) and ?(Sn-C) in the ranges 1489 to 1479 cm-1, 986.2 to 971.2 cm-1 and 568.2 to 550.8 cm-1, respectively. From the 119Sn NMR, both the ligands were suggested to coordinate to the tin atom in a bidentate manner in all three complexes.

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