Synthesis and characterization of bis-thiourea having amino acid derivatives

Imran Fakhar, Bohari Mohd. Yamin, Siti Aishah Hasbullah

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

In this article four new symmetric bis-thiourea derivatives having amino acid linkers were reported with good yield. Isophthaloyl dichloride was used as spacer and L-alanine, L-aspartic acid, L-phenylalanine and L-glutamic acid were used as linkers. Bis-thiourea derivatives were prepared from relatively stable isophthaloyl isothiocyanate intermediate. Newly synthesized bis-thiourea derivatives were characterized by FTIR, H-NMR, 13C-NMR and CHNS-O elemental analysis techniques. Characterization data was in good agreement with the expected derivatives, hence confirmed the synthesis of four new derivatives of bis-thiourea having amino acids.

Original languageEnglish
Title of host publication2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1784
ISBN (Electronic)9780735414464
DOIs
Publication statusPublished - 17 Nov 2016
Event2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016 - Selangor, Malaysia
Duration: 13 Apr 201614 Apr 2016

Other

Other2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016
CountryMalaysia
CitySelangor
Period13/4/1614/4/16

Fingerprint

thioureas
amino acids
synthesis
aspartic acid
nuclear magnetic resonance
glutamic acid
phenylalanine
dichlorides
alanine
spacers

Keywords

  • amino acid
  • Bis-thiourea
  • isophthaloyl isothiocyanate

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Fakhar, I., Mohd. Yamin, B., & Hasbullah, S. A. (2016). Synthesis and characterization of bis-thiourea having amino acid derivatives. In 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium (Vol. 1784). [030012] American Institute of Physics Inc.. https://doi.org/10.1063/1.4966750

Synthesis and characterization of bis-thiourea having amino acid derivatives. / Fakhar, Imran; Mohd. Yamin, Bohari; Hasbullah, Siti Aishah.

2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784 American Institute of Physics Inc., 2016. 030012.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fakhar, I, Mohd. Yamin, B & Hasbullah, SA 2016, Synthesis and characterization of bis-thiourea having amino acid derivatives. in 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. vol. 1784, 030012, American Institute of Physics Inc., 2016 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2016, Selangor, Malaysia, 13/4/16. https://doi.org/10.1063/1.4966750
Fakhar I, Mohd. Yamin B, Hasbullah SA. Synthesis and characterization of bis-thiourea having amino acid derivatives. In 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784. American Institute of Physics Inc. 2016. 030012 https://doi.org/10.1063/1.4966750
Fakhar, Imran ; Mohd. Yamin, Bohari ; Hasbullah, Siti Aishah. / Synthesis and characterization of bis-thiourea having amino acid derivatives. 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Vol. 1784 American Institute of Physics Inc., 2016.
@inproceedings{8211fd2bae594dd4b6b27339ce5617dd,
title = "Synthesis and characterization of bis-thiourea having amino acid derivatives",
abstract = "In this article four new symmetric bis-thiourea derivatives having amino acid linkers were reported with good yield. Isophthaloyl dichloride was used as spacer and L-alanine, L-aspartic acid, L-phenylalanine and L-glutamic acid were used as linkers. Bis-thiourea derivatives were prepared from relatively stable isophthaloyl isothiocyanate intermediate. Newly synthesized bis-thiourea derivatives were characterized by FTIR, H-NMR, 13C-NMR and CHNS-O elemental analysis techniques. Characterization data was in good agreement with the expected derivatives, hence confirmed the synthesis of four new derivatives of bis-thiourea having amino acids.",
keywords = "amino acid, Bis-thiourea, isophthaloyl isothiocyanate",
author = "Imran Fakhar and {Mohd. Yamin}, Bohari and Hasbullah, {Siti Aishah}",
year = "2016",
month = "11",
day = "17",
doi = "10.1063/1.4966750",
language = "English",
volume = "1784",
booktitle = "2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium",
publisher = "American Institute of Physics Inc.",

}

TY - GEN

T1 - Synthesis and characterization of bis-thiourea having amino acid derivatives

AU - Fakhar, Imran

AU - Mohd. Yamin, Bohari

AU - Hasbullah, Siti Aishah

PY - 2016/11/17

Y1 - 2016/11/17

N2 - In this article four new symmetric bis-thiourea derivatives having amino acid linkers were reported with good yield. Isophthaloyl dichloride was used as spacer and L-alanine, L-aspartic acid, L-phenylalanine and L-glutamic acid were used as linkers. Bis-thiourea derivatives were prepared from relatively stable isophthaloyl isothiocyanate intermediate. Newly synthesized bis-thiourea derivatives were characterized by FTIR, H-NMR, 13C-NMR and CHNS-O elemental analysis techniques. Characterization data was in good agreement with the expected derivatives, hence confirmed the synthesis of four new derivatives of bis-thiourea having amino acids.

AB - In this article four new symmetric bis-thiourea derivatives having amino acid linkers were reported with good yield. Isophthaloyl dichloride was used as spacer and L-alanine, L-aspartic acid, L-phenylalanine and L-glutamic acid were used as linkers. Bis-thiourea derivatives were prepared from relatively stable isophthaloyl isothiocyanate intermediate. Newly synthesized bis-thiourea derivatives were characterized by FTIR, H-NMR, 13C-NMR and CHNS-O elemental analysis techniques. Characterization data was in good agreement with the expected derivatives, hence confirmed the synthesis of four new derivatives of bis-thiourea having amino acids.

KW - amino acid

KW - Bis-thiourea

KW - isophthaloyl isothiocyanate

UR - http://www.scopus.com/inward/record.url?scp=85014605631&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85014605631&partnerID=8YFLogxK

U2 - 10.1063/1.4966750

DO - 10.1063/1.4966750

M3 - Conference contribution

VL - 1784

BT - 2016 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium

PB - American Institute of Physics Inc.

ER -