Synthesis and characterisation a series of N-(3,4-dichlorophenyl)-N′-(2,3 and 4-methylbenzoyl)thiourea derivatives

M. Sukeri M Yusof, Rabia'tun Hidayah Jusoh, Wan M. Khairul, Bohari Mohd. Yamin

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Three new compounds, N-(3,4-dichlorophenyl)-N′-(2-methylbenzoyl)thiourea (2a), N-(3,4-dichlorophenyl)-N′-(3-methylbenzoyl)thiourea (2b) and N-(3,4-dichlorophenyl)-N′-(4-methylbenzoyl)thiourea (2c) are isomers which have been successfully synthesised and characterised by typical spectroscopic techniques, namely IR and 1H and 13C multi-nuclear magnetic resonance (NMR). The structure of 2a was determined by single crystal X-ray diffraction method and crystallised in the monoclinic system with space group C2/c, adopting configuration of the molecule is trans-cis. The infrared spectra of these compounds showed four significant stretching vibrations of ν(N{single bond}H), ν(C{double bond, long}O), ν(C{single bond}N) and ν(C{double bond, long}S) at 3261-3279 cm-1, 1662-1680 cm-1, 1345-1379 cm-1 and 688-738 cm-1, respectively. The 13C NMR chemical shift for the thiourea moiety appeared at ca. δC 180 ppm.

Original languageEnglish
Pages (from-to)280-284
Number of pages5
JournalJournal of Molecular Structure
Volume975
Issue number1-3
DOIs
Publication statusPublished - 30 Jun 2010

Fingerprint

Thiourea
Derivatives
Nuclear magnetic resonance
Chemical shift
Isomers
Stretching
Single crystals
Infrared radiation
X ray diffraction
Molecules
single bond

Keywords

  • Carbonylthiourea
  • Crystal structure
  • Methylbenzoylthiourea
  • Thiourea

ASJC Scopus subject areas

  • Spectroscopy
  • Analytical Chemistry
  • Inorganic Chemistry
  • Organic Chemistry

Cite this

Synthesis and characterisation a series of N-(3,4-dichlorophenyl)-N′-(2,3 and 4-methylbenzoyl)thiourea derivatives. / Yusof, M. Sukeri M; Jusoh, Rabia'tun Hidayah; Khairul, Wan M.; Mohd. Yamin, Bohari.

In: Journal of Molecular Structure, Vol. 975, No. 1-3, 30.06.2010, p. 280-284.

Research output: Contribution to journalArticle

Yusof, M. Sukeri M ; Jusoh, Rabia'tun Hidayah ; Khairul, Wan M. ; Mohd. Yamin, Bohari. / Synthesis and characterisation a series of N-(3,4-dichlorophenyl)-N′-(2,3 and 4-methylbenzoyl)thiourea derivatives. In: Journal of Molecular Structure. 2010 ; Vol. 975, No. 1-3. pp. 280-284.
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